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Detail of "177-11-7"

  • CAS Number:
  • 177-11-7
  • Name:

  • 1,4-Dioxa-8-azaspiro[4.5]decane

  • Molecular Structure:
  • Formula:
  • C7H13NO2
  • Molecular Weight:
  • 143.18
  • Synonyms:
  • 8-Aza-1,4-dioxaspiro[4.5]decane;4-Piperidinone ethylene acetal;4-Piperidinone, cyclic 1,2-ethanediyl acetal;4,4-(Ethylenedioxy)piperidine;4-Piperidone ethylene ketal;Piperidin-4-one ethylene ketal;
  • EINECS:
  • 205-868-6
  • Density:
  • 1.12 g/cm3
  • Boiling Point:
  • 211.1 °C at 760 mmHg
  • Flash Point:
  • 81.7 °C
  • Appearance:
  • clear colorless to yellowish liquid
  • Hazard Symbols:
  • IrritantXi
  • Risk Codes:
  • 36/37/38
  • Safety:
  • 26-36-24/25 Details
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CAS No.177-11-7 1,4-Dioxa-8-azaspiro[4.5]decane

Assay:99%min  Appearance:standard  Package:UN DrumStorage:dry,cool  Transportation:by sea or ai...

Supplier:Zouping Mingxing Chemical Co.,Ltd. [ China (Mainland)]

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CAS No.177-11-7 1,4-Dioxa-8-azaspiro[4.5]decane

Assay:97℅  Appearance:Inqury  Package:100g,500g,51...

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CAS No.177-11-7 1,4-Dioxa-8-azaspiro[4.5]decane

Assay:99.5%  Appearance:Powder  Package:25kg/drum

Supplier:Henan Tianfu Chemical Co., Ltd. [ China (Mainland)]

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CAS No.177-11-7 1,4-Dioxa-8-azaspiro[4.5]decane

Assay:98%

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SupplierISO 3875Integral
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CAS No.177-11-7 1,4-Dioxa-8-azaspiro[4.5]decane

1,4-Dioxa-8-azaspiro[4.5]decane

Supplier:Hangzhou Share Chemical Co., Ltd [ China (Mainland)]

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CAS No.177-11-7 1,4-Dioxa-8-azaspiro[4.5]decane

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CAS No.177-11-7 1,4-Dioxa-8-azaspiro[4.5]decane

Supplier:KINHENG CHEMICAL(SHANGHAI)CO., LTD. [ China (Mainland)]

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CAS No.177-11-7 1,4-Dioxa-8-azaspiro[4.5]decane

Chemical Name： 4-Piperidone ethylene ketal Abbr： 4-Piperidone ethylene ketal CAS No.： 177-11-7 Structure： Appearance： Purity： Packing： customer request

Supplier:Shanghai Golden Lily Chem&pharma Co., Ltd [ China (Mainland)]

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CAS No.177-11-7 1,4-Dioxa-8-azaspiro[4.5]decane

Assay:≥98%

Supplier:Nanjing Newst Biotech Co., LTD [ China (Mainland)]

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CAS No.177-11-7 1,4-Dioxa-8-azaspiro[4.5]decane

1,4-Dioxa-8-azaspiro[4.5]decane

Supplier:Synthon Chemicals GmbH & Co. KG [ Germany]

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CAS No.177-11-7 1,4-Dioxa-8-azaspiro[4.5]decane

1-Aminopiperidine.HCL

Supplier:Arham Enterprise [ India]

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CAS No.177-11-7 1,4-Dioxa-8-azaspiro[4.5]decane

4-Piperidone ethyleneketal

Supplier:ALLCHEM LABORATORIES [ India]

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CAS No.177-11-7 1,4-Dioxa-8-azaspiro[4.5]decane

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Supplier:Yancheng Chemhome Chemical Co., Ltd. [ China (Mainland)]

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CAS No.177-11-7 1,4-Dioxa-8-azaspiro[4.5]decane

1,4-DIOXA-8-AZASPIRO[4.7]DECANE

Supplier:Midori Kagaku co.,ltd. [ Japan]

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CAS No.177-11-7 1,4-Dioxa-8-azaspiro[4.5]decane

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CAS No.177-11-7 1,4-Dioxa-8-azaspiro[4.5]decane

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CAS No.177-11-7 1,4-Dioxa-8-azaspiro[4.5]decane

Supplier:Wirtz-Chemieprodukte GmbH [ Germany]

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CAS No.177-11-7 1,4-Dioxa-8-azaspiro[4.5]decane

Supplier:hubei heima company [ China (Mainland)]

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CAS No.177-11-7 1,4-Dioxa-8-azaspiro[4.5]decane

Supplier:HBCChem, Inc. [ United States]

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CAS No.177-11-7 1,4-Dioxa-8-azaspiro[4.5]decane

Supplier:Shanghai DEMO Medical Tech Co.,Ltd [ China (Mainland)]

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CAS No.177-11-7 1,4-Dioxa-8-azaspiro[4.5]decane

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CAS No.177-11-7 1,4-Dioxa-8-azaspiro[4.5]decane

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Reference

Preparation and in vitro and in vivo evaluation of quinolones with selective activity against Gram-positive organisms
Preparation and in vitro and in vivo evaluation of quinolones with selective activity against Gram-positive organisms. Cooper, Curt S.; Klock, Pamela L.; Chu, Daniel T.In this study， 177-11-7 and 130312-02-6 are also used. W.; Hardy, Dwight J.; Swanson, Robert N.; Plattner, Jacob J. (Anti-Infect. Res. Div., Abbott Lab., Abbott Park, IL 60064-3500, USA). J. Med. Chem., 35(8), 1392-8 (English) 1992. CODEN: JMCMAR. ISSN: 0022-2623. DOCUMENT TYPE: Journal CA Section: 28 (Heterocyclic Compounds (More Than One Hetero Atom)) Section cross-reference(s): 10 A series of quinolone derivs. I (R = 2,4-F2C6H3, cyclopropyl, X = CH, N, CF, Y = O, NOH, NOMe, n = 1, 2) were prepd. which contained oximes or substituted oximes. Thus, condensing azadioxaspirononane or -decane II with quinone derivs. III (Z = F, Cl) and hydrolysis gave I (Y = O) which were converted to the oximes. I showed in vivo activity against Staphylococcus aureus. I (R = 2,4-F2C6H3, X = CH, Y = NOH, n = 2) had in vivo activity against Streptococcus pneumoniae. .
A preparation of N-phenyl-heterocyclylcarboxylic acid amide derivatives, useful for treating pain
A preparation of N-phenyl-heterocyclylcarboxylic acid amide derivatives, useful for treating pain. Zheng, Guo Zhu; Brown, Brian S.; Turner, Sean C.; White, Tammie K.; Schmidt, Robert G.; Koenig, John R.; Lee, Chih-Hung (USA ).Chemicals with cas numbers 177-11-7 and 93-05-0 also play role. U.S. Pat. Appl. Publ. US 2005009841 A1 13 Jan 2005,26 pp. (English). (United States of America). CODEN: USXXCO. CLASS: ICM: A61K031-505. ICS: A61K031-44; A61K031-4172. NCL: 514256000; 514357000; 514400000; 544335000; 546336000; 548335500. APPLICATION: US 2003-618016 11 Jul 2003. DOCUMENT TYPE: Patent CA Section: 28 (Heterocyclic Compounds (More Than One Hetero Atom)) Section cross-reference(s): 1, 63 The invention relates to a prepn. of N-phenyl-heterocyclylcarboxylic acid amide derivs. of formula I [wherein: A is (un)substituted oxazolyl, imidazolyl, pyrimidinyl, or pyridinyl, etc.; L is a bond, piperazine-1,4-diyl deriv., or piperidine-1,4-diyl deriv., etc.; R1 and R3 are independently selected from H, alkenyl, alkoxy, alkylthio, or haloalkyl, etc.; R2 is H, alkoxy, alkenyl, alkyl, halogen, or OH, etc.], useful for treating pain. For instance, N-phenyl-heterocyclylcarboxylic acid amide deriv. II (antinociceptive effect: 0.1 mg/kg < ED50 < 150 mg/kg) was prepd. via amination of 2-bromo-3-chloropyridine by 1,2,3,6-tetrahydro-4-pyridinecarboxylic acid and subsequent amidation of the obtained bipyridinecarboxylic acid deriv. III by 4-tert-butylaniline. .
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