Detail of > 177036-94-1
- CAS Number:
- 177036-94-1
- Name:
Benzenepropanoic acid, a-[(4,6-dimethyl-2-pyrimidinyl)oxy]-b-methoxy-b-phenyl-, (aS)-
- Superlist Name:
- Ambrisentan
- Formula:
- C22H22N2O4
- Molecular Structure:
![Molecular Structure of 177036-94-1 (Benzenepropanoic acid, a-[(4,6-dimethyl-2-pyrimidinyl)oxy]-b-methoxy-b-phenyl-, (aS)-)](http://www.lookchem.com/300w/2010/076/177036-94-1.jpg)
- Synonyms:
- Benzenepropanoicacid, a-[(4,6-dimethyl-2-pyrimidinyl)oxy]-b-methoxy-b-phenyl-, (S)-;BSF208075;LU 208075;
- Molecular Weight:
- 378.42
- Density:
- 1.228 g/cm3
- Boiling Point:
- 551.1 °C at 760 mmHg
- Flash Point:
- 287.1 °C
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Reference
- Treatment of pulmonary hypertension: endothelin-receptor antagonists
- All Rights Reserved. Treatment of pulmonary hypertension: endothelin-receptor antagonists. Hoeper, Marius M. (Abteilung Pneumologie, Medizinische Hochschule Hannover, Hannover D-30623, Germany). Deutsche Medizinische Wochenschrift, 131(49, Suppl.There are some reagents with their cas registry numbers 177036-94-1 and 184036-34-8 are used in this study. 9), S308-S310 (German) 2006 Georg Thieme Verlag. CODEN: DMWOAX. ISSN: 0012-0472. DOCUMENT TYPE: Journal; General Review CA Section: 1 (Pharmacology) A review on treatment of pulmonary arterial hypertension by endothelin receptor antagonists. Biol. of the endothelin system, pathophysiol., and prognostic significance of endothelin-1 in pulmonary hypertension are described. Therapy of idiopathic pulmonary arterial hypertension and other types of pulmonary hypertension by the dual endothelin-receptor antagonist bosentan and treatment of pulmonary arterial hypertension with selective endothelin-A receptor antagonists (sitaxsentan and ambrisentan) are discussed. .
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