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Detail of "1786-81-8"

  • MSDS Download
  • CAS Number:
  • 1786-81-8
  • Name:

  • Propanamide,N-(2-methylphenyl)-2-(propylamino)-, hydrochloride (1:1)

  • Superlist Name:
  • Propitocaine hydrochloride
  • Molecular Structure:
  • Formula:
  • C13H20N2O.HCl
  • Molecular Weight:
  • 256.77
  • Synonyms:
  • Citanest hydrochloride;L 67;L 67hydrochloride;Prilocaine chloride;Propitocainehydrochloride;Xylonest;a-(Propylamino)-2-methylpropionanilide hydrochloride;Prilocaine HCL;Propanamide,N-(2-methylphenyl)-2-(propylamino)-, monohydrochloride (9CI);o-Propionotoluidide,2-(propylamino)-, monohydrochloride (8CI);2-(Propylamino)-o-propionotoluididehydrochloride;Citanest Plain;
  • EINECS:
  • 217-244-0
  • Boiling Point:
  • 361.6 °C at 760 mmHg
  • Flash Point:
  • 134.3 °C
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CAS No.1786-81-8 Propitocaine hydrochlorideCompetitive Product

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CAS No.1786-81-8 Propitocaine hydrochloride

  Appearance:White powder

Chemical Name：Propitocaine hydrochloride Other Name：N-(2-Methylphenyl)-2-propylamino-propanamide Molecular Formula: C13H21ClN2O Molecular Weight: 256.77

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Formula:C13H20N2O.HCl Molecular Weight: 256.77

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Reference

The effects of commercial local anesthetic solutions on the isolated rabbit ear artery
The effects of commercial local anesthetic solutions on the isolated rabbit ear artery. Gerke, D. C.; Frewin, D. B.; Waterson, J. G. (Dep. Hum. Physiol. Pharmacol., Univ. Adelaide, Adelaide, Aust.). Aust. Dent. J., 22(4), 289-94 (English) 1977. CODEN: ADEJA2. ISSN: 0045-0421. DOCUMENT TYPE: Journal CA Section: 1 (Pharmacodynamics) The response of an isolated artery prepn. to com. local anesthetic solns. contg. either prilocaine-HCl [1786-81-8] or lignocaine [137-58-6] in the presence of adrenaline [51-43-4] or noradrenaline [51-41-2] was examd. In low concns. both local anesthetics augmented the constrictor response to adrenaline, whereas at higher concns. the effect of adrenaline was significantly depressed by them. In contrast, the vasoconstrictor response to noradrenaline was not potentiated by low concns. of lignocaine, although higher concn. levels caused a significant decrease in the vasoconstrictor effect of noradrenaline.
A rapid spectrophotometric assay of amide type dental anesthetic agents
A rapid spectrophotometric assay of amide type dental anesthetic agents. De Freitas, J. F. (Aust. Dent. Stand. Lab., Melbourne, Aust.). Aust. Dent. J., 22(3), 182-9 (English) 1977. CODEN: ADEJA2. DOCUMENT TYPE: Journal CA Section: 64 (Pharmaceutical Analysis) A rapid assay method for lignocaine-HCl (I-HCl) [73-78-9] involved spectrophotometric measurement of a Cu complex formed in alk. medium. The method was extended to other amide-type dental anesthetics, i.e., prilocaine-HCl [1786-81-8], mepivacaine-HCl [1722-62-9], pyrrocaine-HCl [7690-40-6], and tolycaine [7210-92-6]. Spectral absorption maxima were characteristic and were at 570 nm for I and at 610, 600, 620, and 640 nm, resp., for the remaining 4 anesthetics. The Beer-Lambert law was obeyed over 0-150 mg of anesthetic/100 mL. Various additives did not interfere with the detn.
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