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CAS No.: | 18437-58-6 |
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Name: | 4-Amino-2-picoline |
Article Data: | 33 |
Molecular Structure: | |
Formula: | C6H8N2 |
Molecular Weight: | 108.143 |
Synonyms: | 2-Picoline,4-amino- (7CI,8CI);2-Methyl-4-aminopyridine;2-Methyl-4-pyridinamine;4-Amino-2-methylpyridine;4-Amino-a-picoline; |
EINECS: | -0 |
Density: | 1.068 g/cm3 |
Melting Point: | 93-97 °C |
Boiling Point: | 247.4 °C at 760 mmHg |
Flash Point: | 126.9 °C |
Appearance: | light yellow cryst |
Hazard Symbols: | Xn,T,Xi |
Risk Codes: | 22-37/38-41-36/37/38-20/21/22 |
Safety: | 26-36/39-36 |
PSA: | 38.91000 |
LogP: | 1.55340 |
The 4-Amino-2-picoline with cas registry number of 18437-58-6 has an appearance of light yellow cryst. It is also known as 4-Amino-2-methylpyridine. Both its systematic name and IUPAC name are the same which is called 2-methylpyridin-4-amine. This chemical belongs to the categories as follows: variousamine; Amines; blocks; Pyridines; Amines and Anilines; Heterocycles.
The Physical properties about this chemical are: (1)ACD/LogP: 0.72; (2)# of Rule of 5 Violations: 0; (3)ACD/BCF (pH 5.5): 1; (4)ACD/BCF (pH 7.4): 1; (5)ACD/KOC (pH 5.5): 1; (6)ACD/KOC (pH 7.4): 1; (7)#H bond acceptors: 2; (8)#H bond donors: 2; (9)#Freely Rotating Bonds: 1; (10)Index of Refraction: 1.574; (11)Molar Refractivity: 33.4 cm3; (12)Molar Volume: 101.2 cm3; (13)Surface Tension: 46.9 dyne/cm; (14)Density: 1.068 g/cm3; (15)Flash Point: 126.9 °C; (16)Enthalpy of Vaporization: 48.46 kJ/mol; (17)Boiling Point: 247.4 °C at 760 mmHg; (18)Vapour Pressure: 0.0256 mmHg at 25°C.
Preparation of 4-Amino-2-picoline: this chemical can be made by 6c-methoxy-hex-5-en-3-yn-2-one using reagents NH3 at temperature 100 ℃ and pressure 5171.48 with reaction time 14 hours. The yield is about 86%.
Uses of 4-Amino-2-picoline: it can be used to prepare 2-methyl-pyridin-4-ol; nitrate using reagents HNO3, NaNO2 and Solvent H2O below 20 deg C. The yield is about 40%.
When you are using this chemical, please be cautious about it as the following:
If you are using this chemical, wear suitable protective clothing, eye / face protection, because it is irritating to eyes, respiratory system and skin and harmful by inhalation, in contact with skin and if swallowed. In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
You can still convert the following datas into molecular structure:
(1)SMILES: n1ccc(N)cc1C;
(2)InChI: InChI=1/C6H8N2/c1-5-4-6(7)2-3-8-5/h2-4H,1H3,(H2,7,8);
(3)InChIKey: GNCLPNMQEGMNTG-UHFFFAOYAB