Detail of "18786-24-8"

Reference

Alkaloids of Rauvolfia caffra sond

Alkaloids of Rauvolfia caffra sond. I. Phytochemical and toxicological studies. Madati, P. J.; Kayani, M. J.; Pazi, H. A. M.; Nyamgenda, A. F. D. (Cent. Gov. Chem. Lab., Dar es Salaam, Tanzania). Planta Med., 32(3), 258-67 (English) 1977. CODEN: PLMEAA. DOCUMENT TYPE: Journal CA Section: 63 (Pharmaceuticals) Section cross-reference(s): 11 Phytochem. assays of R. caffra (Msesewe) showed that total alkaloid content was highest (3.05%) in young root bark. The av. individual alkaloid per cents in the root bark were: ajmalicine (I) [483-04-5] 0.16, ajmaline [4360-12-7] 1.25, rescinnamine [24815-24-5] 0.02, reserpiline [131-02-2] 0.01, reserpine (II) [50-55-5] 0.08, and serpentine [18786-24-8] 1.09. Chronic toxicity studies of the alkaloids in rats and rabbits were not very informative.

Three alkaloids as selective destroyers of the proliferative capacity of cancer cells

Three alkaloids as selective destroyers of the proliferative capacity of cancer cells. Beljanski, M.; Beljanski, M. S. (Lab. Pharmacodyn., Fac. Pharm., Chatenay-Malabry 92290, Fr.). IRCS Med. Sci., 12(7), 587-8 (English) 1984. CODEN: IMSCE2. DOCUMENT TYPE: Journal CA Section: 1 (Pharmacology) At appropriate concns., alstonine [642-18-2], serpentine [18786-24-8], and sempervirine [549-92-8] selectively and completely destroyed the proliferative capacity of many different cancer cells without affecting the proliferative capacity of normal cells. The proliferative capacity of cancer cells and of normal cells was unaffected by ajmalicine [483-04-5], ajmaline [4360-12-7], or reserpine [50-55-5].