Reference

Determination of Log Po/w for Catechins and Their Isomers, Oligomers, and Other Organic Compounds by Stationary Phase Controlled High Speed Countercurrent Chromatography

Determination of Log Po/w for Catechins and Their Isomers, Oligomers, and Other Organic Compounds by Stationary Phase Controlled High Speed Countercurrent Chromatography. Shibusawa, Yoichi; Shoji, Atsushi; Yanagida, Akio; Shindo, Heisaburo; Tagashira, Motoyuki; Ikeda, Mitsuo; Ito, Yoichiro (Division of Structural Biology and Analytical Science, Tokyo University of Pharmacy and Life Science, Tokyo 1432-1, Japan). Journal of Liquid Chromatography & Related Technologies, 28(17), 2819-2834 (English) 2005 Taylor & Francis, Inc. CODEN: JLCTFC. ISSN: 1082-6076. DOCUMENT TYPE: Journal CA Section: 9 (Biochemical Methods) A new technique, stationary phase vol. controlled high speed counter-current chromatog. (HSCCC), was used to det. the octanol-water partition coeffs. (Po/w) of catechins and their isomers, oligomers, and other org. compds. The stationary phase vol. in the CCC column was effectively controlled under hydrodynamic equil. system. The log Po/w values ranging from -1.35 to +3.60 were measured within 21 min using this new HSCCC technol. The linear relationship (correlation coeff. value, r = 0. 130405-40-2 and 18829-70-4 which are cas registry numbers of substances are two of reagents here.993) was obsd. between log Po/w values obtained by the shake-flask method and those values by the HSCCC method. In this technique, it is possible to inject multiple samples successively into the CCC column at short intervals to measure their retention times without renewing the stationary phase vol. .

Phytotoxic and Antimicrobial Activities of Catechin Derivatives

Phytotoxic and Antimicrobial Activities of Catechin Derivatives. Veluri, Ravikanth; Weir, Tiffany L.; Bais, Harsh Pal; Stermitz, Frank R.; Vivanco, Jorge M. (Department of Horticulture and Landscape Architecture and Department of Chemistry, Colorado State University, Fort Collins, CO 80523-1173, USA). Journal of Agricultural and Food Chemistry, 52(5), 1077-1082 (English) 2004 American Chemical Society. CODEN: JAFCAU. ISSN: 0021-8561. DOCUMENT TYPE: Journal CA Section: 5 (Agrochemical Bioregulators) (±)-Catechin is a potent phytotoxin, with the phytotoxicity due entirely to the (-)-catechin enantiomer. (+)-Catechin, but not the (-)-enantiomer, has antibacterial and antifungal activities. Tetramethoxy, pentaacetoxy, and cyclic derivs. of (±)-catechin retained phytotoxicity. The antioxidant properties of catechins are not a detg. factor for phytotoxicity. A similar conclusion was reached for the antimicrobial properties.There are some commonly used reagents with their cas registry numbers 18829-70-4 and 132125-04-3 in this article. Centaurea maculosa (spotted knapweed) exudes (±)-catechin from its roots, but the flavanol is not re-absorbed and hence the weed is not affected. The much less polar tetramethoxy deriv. may, however, be absorbed and hence be able to cause toxicity. Because of the combination of phytotoxicity and antimicrobial activity, (±)-catechin could be a useful natural herbicide and antimicrobial. .