CAS No.1889-71-0,4'-Chloro-2-phenylacetophenone Suppliers,MSDS download

Products Categories

Pharmaceutical (39)
Organic Chemicals (16)
Others (14)
Reagent (3)
Materials (1)
Synthetic Flavours & Fragrances (1)

Basic Information

Molecular Structure:
CAS No.:	1889-71-0
Name:	4'-Chloro-2-phenylacetophenone
Article Data:	105

Formula:	C₁₄H₁₁ClO
Molecular Weight:	230.694
Synonyms:	Acetophenone,4'-chloro-2-phenyl- (6CI,7CI,8CI);1-(4-Chlorophenyl)-2-phenyl-1-ethanone;1-(4-Chlorophenyl)-2-phenylethanone;4-Chlorophenyl benzyl ketone;Benzyl 4-chlorophenyl ketone;Benzylp-chlorophenyl ketone;NSC 32891;NSC 99455;p-Chlorophenyl benzyl ketone;
Density:	1.191 g/cm³
Melting Point:	103-107 °C(lit.)
Boiling Point:	365.4 °C at 760 mmHg
Flash Point:	197.6 °C
Hazard Symbols:	Xi; N
Risk Codes:	41-43-51/53
Safety:	26-39-60-61
Transport Information:	UN 3077 9/PG 3
PSA:	17.07000
LogP:	3.76540

Synthetic route

: α-benzyl-4,4'-dichlorobenzoin

A: 4254-20-0
4,4'-dichlorobenzoin

B: 1889-71-0
4'-chloro-2-phenylacetophenone

Conditions

Conditions	Yield
With tetra-n-butylammonium cyanide In tetrahydrofuran for 1.5h; Ambient temperature;	A 12% B 100%

: 72867-63-1
N-[1-(4-Chloro-phenyl)-1-cyano-2-phenyl-ethyl]-N-phenyl-benzamide

: 1889-71-0
4'-chloro-2-phenylacetophenone

Conditions

Conditions	Yield
With potassium hydroxide In ethanol; water Heating;	99%

: 28122-82-9
S-phenyl 4-chlorobenzothioate

: 62673-31-8
benzyl(bromo)zinc

: 1889-71-0
4'-chloro-2-phenylacetophenone

Conditions

Conditions	Yield
With (phenyl)(bis-triphenylphosphine)palladium(II) chloride In tetrahydrofuran; toluene at 20℃; for 1h; Fukuyama Coupling; Inert atmosphere;	98%

: 100-03-8
4-chlorobenzenesulfinic acid

: 140-29-4
phenylacetonitrile

: 1889-71-0
4'-chloro-2-phenylacetophenone

Conditions

Conditions	Yield
With [2,2]bipyridinyl; sulfuric acid; water; palladium diacetate In 2-methyl-propan-1-ol at 100℃; for 6h; Inert atmosphere;	95%

: 114679-00-4
2-(4-chlorophenyl)-2-oxo-1-phenylethyl benzoate

: 1889-71-0
4'-chloro-2-phenylacetophenone

Conditions

Conditions	Yield
With palladium(II) trifluoroacetate; hydrogen; [(4S)-4-[5-bis(3,5-di-tert-butyl-4-methoxyphenyl)phosphanyl-1,3-benzodioxol-4-yl]-4,5,6,7-tetrahydro-1,3-benzodioxol-5-yl]-bis(3,5-di-tert-butyl-4-methoxyphenyl)phosphane In acetone at 60℃; under 45004.5 Torr; for 24h; Glovebox; Autoclave; chemoselective reaction;	94%

: 119267-71-9
2-(4-chlorophenyl)-2-oxo-1-phenylethyl acetate

: 1889-71-0
4'-chloro-2-phenylacetophenone

Conditions

Conditions	Yield
With tris(bipyridine)ruthenium(II) dichloride hexahydrate; diethyl 2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate; triethylamine In acetonitrile at 20℃; for 1h; Inert atmosphere; UV-irradiation;	92%

: 100-39-0
benzyl bromide

: 122-01-0
4-chloro-benzoyl chloride

: 1889-71-0
4'-chloro-2-phenylacetophenone

Conditions

Conditions	Yield
With bis-triphenylphosphine-palladium(II) chloride; zinc In 1,2-dimethoxyethane for 0.333333h; Ambient temperature;	90%
With bis-triphenylphosphine-palladium(II) chloride; zinc In 1,2-dimethoxyethane at 20℃; for 0.5h; Inert atmosphere; Schlenk technique;

: C7H7ClZn*Cl3LiMg

: 122-01-0
4-chloro-benzoyl chloride

: 1889-71-0
4'-chloro-2-phenylacetophenone

Conditions

Conditions	Yield
With iron(II) chloride In tetrahydrofuran at 25℃; for 0.5h; Reagent/catalyst; Solvent; Inert atmosphere; Schlenk technique;	90%

: 3-(4-chlorophenyl)-3-oxo-2-phenylpropanal

: 1889-71-0
4'-chloro-2-phenylacetophenone

Conditions

Conditions	Yield
With ethylenediamine In tetrahydrofuran for 4h; Heating;	88%

: 108-90-7
chlorobenzene

: 103-80-0
phenylacetyl chloride

: 1889-71-0
4'-chloro-2-phenylacetophenone

Conditions

Conditions	Yield
With zinc(II) oxide at 20℃; for 0.0833333h; Friedel-Crafts acylation;	85%
With aluminum (III) chloride In dichloromethane at 0 - 20℃;	79%
With aluminium trichloride at 20℃;	74%

Total:69 Page 1 of 2 1 2 Next>>

Post a RFQ

Cas No.:

Product Name:

Quantity:

Email:

Company name:

Valid Period:

Detailed Requirements:

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

What can I do for you?
Get Best Price

Get Best Price for 1889-71-0

Specification

The Ethanone,1-(4-chlorophenyl)-2-phenyl-, with CAS registry number 1889-71-0, belongs to the following product category: Aromatic Ketones (substituted). It has the systematic name of 1-(4-chlorophenyl)-2-phenylethanone. And the chemical formula of this chemical is C₁₄H₁₁ClO. This chemical should be stored in cool, dry place.

Physical properties of Ethanone,1-(4-chlorophenyl)-2-phenyl-: (1)ACD/LogP: 3.86; (2)# of Rule of 5 Violations: 0; (3)#H bond acceptors: 1; (4)#H bond donors: 0; (5)#Freely Rotating Bonds: 3; (6)Polar Surface Area: 17.07 Å²; (7)Index of Refraction: 1.593; (8)Molar Refractivity: 65.66 cm³; (9)Molar Volume: 193.6 cm³; (10)Polarizability: 26.03×10^-24cm³; (11)Surface Tension: 44.6 dyne/cm; (12)Enthalpy of Vaporization: 61.17 kJ/mol; (13)Vapour Pressure: 1.57E-05 mmHg at 25°C.

Preparation: this chemical can be prepared by phenylacetyl chloride and chlorobenzene. This reaction will need reagent AlCl₃. The reaction temperature is 20°C. The yield is about 74%.

Uses of Ethanone,1-(4-chlorophenyl)-2-phenyl-: it can be used to produce 2-bromo-1-(4-chloro-phenyl)-2-phenyl-ethanone. This reaction will need reagents tetrachloromethane, bromine.

When you are using this chemical, please be cautious about it as the following:
The Ethanone,1-(4-chlorophenyl)-2-phenyl- has risk of serious damage to the eyes. This chemical may cause sensitization by skin contact. And it is toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment, so avoid release to the environment. Refer to special instructions / safety data sheets. If contact with eyes, rinse immediately with plenty of water and seek medical advice. This material and its container must be disposed of as hazardous waste.

You can still convert the following datas into molecular structure:
(1)SMILES: O=C(c1ccc(Cl)cc1)Cc2ccccc2
(2)InChI: InChI=1/C14H11ClO/c15-13-8-6-12(7-9-13)14(16)10-11-4-2-1-3-5-11/h1-9H,10H2
(3)InChIKey: DXVALSKCLLBZEB-UHFFFAOYAA
(4)Std. InChI: InChI=1S/C14H11ClO/c15-13-8-6-12(7-9-13)14(16)10-11-4-2-1-3-5-11/h1-9H,10H2
(5)Std. InChIKey: DXVALSKCLLBZEB-UHFFFAOYSA-N