CAS No.193551-21-2,trans-1-(4-HYDROXYCYCLOHEXYL)-4-(4-FLUOROPHENYL)-5-(2-METHOXYPY-RIMIDIN-4-YL)IMIDAZOLE Suppliers

CAS Number:
193551-21-2
Name:
trans-1-(4-HYDROXYCYCLOHEXYL)-4-(4-FLUOROPHENYL)-5-(2-METHOXYPY-RIMIDIN-4-YL)IMIDAZOLE
Superlist Name:
SB-239063
Formula:
C₂₀H₂₁FN₄O₂
Molecular Weight:
368.41
Hazard Symbols:
A poison by ingestion.
Safety:
A poison by ingestion. When heated to decomposition it emits toxic vapors of NO_x and F⁻.Details

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Compositions and methods for preventing and treating skin and hair conditions: Compositions and methods for preventing and treating skin and hair conditions. David, Nathaniel E. (VVII NewCo 2003, Inc., USA). U.S. Pat. Appl.In this study，193551-21-2 is also used. Publ. US 2005203111 A1 15 Sep 2005, 16 pp. (English). (United States of America). CODEN: USXXCO. CLASS: ICM: A61K031-517. ICS: A61K031-4745; A61K031-4196. APPLICATION: US 2004-799867 12 Mar 2004. DOCUMENT TYPE: Patent CA Section: 1 (Pharmacology) Section cross-reference(s): 7, 62, 63 The present invention discloses compns. and methods for the prevention and treatment of skin and hair diseases, such as, for example, alopecia, psoriasis, and keloids. In one embodiment, the present invention discloses a method for preventing and treating hair loss by applying locally to a region lacking hair a p38a MAP kinase inhibitor. The p38a MAP kinase inhibitor is preferably formulated as a gel, ointment, spray or soln. that can be applied topically, transdermally, or s.c. to the targeted region. The p38 inhibitor is esp. RDP-58, AMG-548, BIRB-796, CNI-1493, VX-702 or VX-745. .

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