Detail of "1956-23-6"

CAS Number:
1956-23-6
Name:
Benzo[b]thiophene-3-propanoicacid, a-amino-
Molecular Structure:
Formula:
C11H11 N O2 S
Molecular Weight:
0
Synonyms:
Benzo[b]thiophene-3-alanine(7CI); Benzo[b]thiophene-3-propionic acid, a-amino- (8CI); DL-Thiotryptophan; b-(Benzothien-3-yl)-DL-alanine

Please post your buying leads,so that our qualified suppliers will soon contact you!
*Required Fields

preparation of benzothieno- and benzofuranopyridinecarboxylates as psychotropics: Ueki, Showa; Kawakubo, Hiromu; Okazaki, Katsuya; Nagatani, Tadashi (Asahi Kasei Kogyo K.K., Japan). U.S. US 5126448 A 30 Jun 1992, 30 pp. Cont.-in-part of U.S. Ser. No. 219,540, abandoned. (United States of America). CODEN: USXXAM. CLASS: ICM: C07D243-08. ICS: C07D413-04; C07D471-04. NCL: 540575000. APPLICATION: US 89-414892 29 Sep 1989. PRIORITY: JP 86-241226 13 Oct 1986; JP 86-242164 14 Oct 1986; US 88-219540 13 Jun 1988. DOCUMENT TYPE: Patent CA Section: 28 (Heterocyclic Compounds (More Than One Hetero Atom)) Section cross-reference(s): 1 Title compds. I [R1 = (substituted) C1-6 alkoxy, -NH2, -HNNH2, 6- or 7-membered heterocyclyl ring contg. at least one N; R1 = alkoxy when pyridine ring is unsatd.; R2, R3 = halo, (substituted) alkyl, -aryl, -alkenyl, -acyl, -aroyl; A = O, S; m, n = 0-4; R2 and R3 may be different when m and n 3 2] and their 1,2,3,4-tetrahydropyridine derivs. were prepd. as psychotropics useful for the control of anxiety. Thus Et 3-(benzo[b]thiophen-3-yl)-2-nitropropionate (prepn. given) was reduced to the amine hydrochloride by Fe/HCl. The amine was refluxed with an aq. EtOH and H2CO to give I (R1 = OEt; R2-R3 = H; A = S; satd.In this experiment, several chemicals are used like 1956-23-6 pyridine ring). The latter, at 10 mg/kg i.v. in rats, showed good antianxiety activity. .