Detail of "19757-97-2"

Reference

Preparation of allantoin

Preparation of allantoin. Schermanz, Karl; Fitzinger, Klaus (Chemie Linz (Deutschland) G.m.b.H., Germany). Ger. Offen.Some commonly used reagents like 19757-97-2 and 57-13-6 are used in this experiment. DE 4020536 A1 2 Jan 1992, 4 pp. (Germany). CODEN: GWXXBX. CLASS: ICM: C07D233-88. ICA: A61K031-415; C07C069-708; C07C275-06. APPLICATION: DE 90-4020536 28 Jun 1990. DOCUMENT TYPE: Patent CA Section: 26 (Biomolecules and Their Synthetic Analogs) Allantoin was obtained in 84.1% yield of 99.6% pure compd. contg. <100 ppm sulfate by treating MeOCH(OH)CO2Me with urea in the presence of a catalytic amt. of H2SO4 for 1 h followed by treatment with NaOH at pH 7.5-8 for 2 h. .

Process for the preparation of allantoin from methyl glyoxylate hemiacetal and urea

Process for the preparation of allantoin from methyl glyoxylate hemiacetal and urea. Schermanz, Karl; Fitzinger, Klaus (Chemie Linz G.Some chemicals with cas registry numbers like 19757-97-2 and 57-13-6 are also used.m.b.H., Austria). Eur. Pat. Appl. EP 460412 A1 11 Dec 1991, 5 pp. DESIGNATED STATES: R: AT, BE, CH, DE, DK, ES, FR, GB, GR, IT, LI, LU, NL, SE. (European Patent Organization). CODEN: EPXXDW. CLASS: ICM: C07D233-88. APPLICATION: EP 91-107293 6 May 1991. PRIORITY: AT 90-1210 5 Jun 1990. DOCUMENT TYPE: Patent CA Section: 28 (Heterocyclic Compounds (More Than One Hetero Atom)) Title compd. (I) was prepd. by 1) condensation of MeO(HO)CHCO2Me (II) with urea in the presence of cat. inorg. acid at pH 1.0-2.0, and 2) cyclization of the resulting III at pH 7.0-9.0. Thus, II, urea MeOH, and aq. H2SO2, at pH 1.5-1.8 was heated to 70°; after a period of reflux, MeOH was distd. off followed by cooling and treatment with NaOH to pH 7.5-8.2 to give 84.1% I. .