Detail of "1982-37-2"

Reference

Colorimetric estimation of methdilazine hydrochloride

Colorimetric estimation of methdilazine hydrochloride. Kamalapurkar, O. S.; Menezes, Constancio (Pharm. Res. Lab., Goa Coll. Pharm., Goa 403 001, India). Indian Drugs, 22(2), 97-8 (English) 1984. CODEN: INDRBA. ISSN: 0019-462X. DOCUMENT TYPE: Journal CA Section: 64 (Pharmaceutical Analysis) Methdilazine (I) [1982-37-2] as the hydrochloride was detd. by reaction with morpholine [110-91-8] and Br to give a stable blue color which exhibits max. absorbance at 655 nm. It obeys Beer's Law in the concn. range of 9-20 m/mL. Recoveries ranged 98.3-100.5%.

Effect of H1 blockers alone and in combination with morphine to produce antinociception in mice

Effect of H1 blockers alone and in combination with morphine to produce antinociception in mice. Sun, C. L. J.; Hui, F. W.; Hanig, J. P. (Div. Drug Biol., Food Drug Adm., Washington, DC 20204, USA). Neuropharmacology, 24(1), 1-4 (English) 1985. CODEN: NEPHBW. ISSN: 0028-3908. DOCUMENT TYPE: Journal CA Section: 1 (Pharmacology) Antinociception was assessed in male CD-1 mice by a modification of Haffner's tail-clamp procedure. The H1 blockers, including an ethylenediamine (pyrilamine maleate [59-33-6]), an ethanolamine (diphenhydramine [58-73-1]), a phenothiazine (methdilazine [1982-37-2]), a piperazine (cyclizine [82-92-8]) and an alkylamine (chlorpheniramine maleate [113-92-8]), all produced antinociception when given alone to mice and also caused potentiation when combined with morphine [57-27-2].