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CAS No.: | 2001-95-8 |
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Name: | Valinomycin |
Article Data: | 2 |
Molecular Structure: | |
Formula: | C54H90 N6 O18 |
Molecular Weight: | 1111.34 |
Synonyms: | 1,7,13,19,25,31-Hexaoxa-4,10,16,22,28,34-hexaazacyclohexatriacontane-2,5,8,11,14,17,20,23,26,29,32,35-dodecone,3,6,9,15,18,21,27,30,33-nonaisopropyl-12,24,36-trimethyl- (7CI);Cyclo(D-a-hydroxyisovaleryl-D-valyl-L-lactoyl-L-valyl-D-a-hydroxyisovaleryl-D-valyl-L-lactoyl-L-valyl-D-a-hydroxyisovaleryl-D-valyl-L-lactoyl-L-valyl);NSC 122023;Valinomicin; |
EINECS: | 217-896-6 |
Density: | 1.060 |
Melting Point: | 186-190 °C |
Boiling Point: | 1321.6 °C at 760 mmHg |
Flash Point: | 753.1 °C |
Solubility: | DMSO: ≥10 mg/mL in water |
Appearance: | White solid. |
Hazard Symbols: | Xn |
Risk Codes: | 27/28 |
Safety: | Poison by ingestion, skin contact, intraperitoneal, and subcutaneous routes. When heated to decomposition it emits toxic fumes of NOx. |
Transport Information: | UN 2811 6 |
PSA: | 332.40000 |
LogP: | 4.31610 |
Product Name: Valinomycin (2001-95-8)
Molecular Formula: C54H90N6O18
Molecular Weight: 1111.32g/mol
Mol File: 2001-95-8.mol
Einecs: 217-896-6
Appearance: Shiny crystalline solid
Melting Point: 186-190 °C
Boiling point: 1321.6 °C at 760 mmHg
Storage Temperature: 2-8°C
Flash Point: 753.1 °C
Density: 1.06 g/cm3
Water Solubility: ≥10 mg/mL in water
Synonyms of Valinomycin (2001-95-8): 1,7,13,19,25,31-hexaoxa-4,10,16,22,28,34-hexaazacyclohexatriacontane-2,5,8,11, ; 14,17,20,23,26,29,32,35-dodecone,12,24,36-trimetyl-3,6,9,15,18,21,27,30,33-non ; akis(1-methylethyl)-[qr] ; aleryl-d-valyl-l-lactoyl-l-valyl-d-alpha-hydroxyisovaleryl-d-valyl-l-lactoyl-l ; antibioticn-329b ; cyclic(d-alpha-hydroxyisovaleryl-d-valyl-l-lactoyl-l-valyl-d-alpha-hydroxyisov ; nsc122023 ; nsc122023 .
Valinomycin (2001-95-8) used as an insecticide and nematocide.
Valinomycin (2001-95-8) is highly toxic orally.
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
mouse | LD50 | intraperitoneal | 390ug/kg (0.39mg/kg) | National Cancer Institute Screening Program Data Summary, Developmental Therapeutics Program. Vol. JAN1986, | |
mouse | LD50 | intravenous | 180ug/kg (0.18mg/kg) | Cancer Research. Vol. 46, Pg. 5518, 1986. | |
mouse | LD50 | oral | 2500ug/kg (2.5mg/kg) | "Antibiotics: Origin, Nature, and Properties," Korzyoski, T., et al., eds., Washington, DC, American Soc. for Microbiology, 1978Vol. 1, Pg. 325, 1978. | |
mouse | LD50 | subcutaneous | 4140ug/kg (4.14mg/kg) | Antibiotics and Chemotherapy Vol. 12, Pg. 482, 1962. | |
rabbit | LD50 | skin | 5mg/kg (5mg/kg) | BEHAVIORAL: TREMOR BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD | Drug and Chemical Toxicology. Vol. 8, Pg. 451, 1985. |
rat | LD50 | intraperitoneal | 800ug/kg (0.8mg/kg) | BEHAVIORAL: TREMOR BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD | Drug and Chemical Toxicology. Vol. 8, Pg. 451, 1985. |
rat | LD50 | oral | 4mg/kg (4mg/kg) | BEHAVIORAL: TREMOR BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD | Drug and Chemical Toxicology. Vol. 8, Pg. 451, 1985. |
EPA Extremely Hazardous Substances List. Reported in EPA TSCA Inventory.
Poison by ingestion, skin contact, intraperitoneal, and subcutaneous routes. When heated to decomposition it emits toxic fumes of NOx.
When heated to decomposition, VALINOMYCIN emits toxic fumes of nitrogen oxides.
Safety Information of Valinomycin (2001-95-8):
Hazard Codes: Xn,T
Risk Statements: 27/28-36/37/38
27: Very Toxic in contact with skin
28: Very Toxic if swallowed
36: Irritating to the eyes
37: Irritating to the respiratory system
38: Irritating to the skin
Safety Statements: 36-45-36/37-28-37/39-26
26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
28: After contact with skin, wash immediately with plenty of ... (to be specified by the manufacturer)
36: Wear suitable protective clothing
37: Wear suitable gloves
39: Wear eye/face protection
45: In case of accident or if you feel unwell, seek medical advice immediately (show label where possible)