Detail of "20099-89-2"

Reference

Photochemistry of cyclic enones

Photochemistry of cyclic enones. Part 9. Effect of electron-donating and -attracting substituents on the ene in the [2 + 2] cycloaddition reactions of 3-phenyl-5-(prop-2-enyl)cyclopentenones. Clements, Michael T. M.; Crowley, Kevin J.; Kavanagh, Pierce V.; Lennon, Mary A.; McMurry, T. Brian H.; Napier, Michael P. (Univ. Chem.There are some reagents with their cas registry numbers 137936-61-9 and 20099-89-2 are used in this study. Lab., Trinity Coll., Dublin, Ire.). J. Chem. Res., Synop., (11), 318 (English) 1991. CODEN: JRPSDC. ISSN: 0308-2342. DOCUMENT TYPE: Journal CA Section: 24 (Alicyclic Compounds) The effect of MeO or cyano group at the 4-position of the arom. ring in the 5-(3-phenylprop-2-enyl) side-chain attached to a 3-phenylcyclopent-2-enone during photochem. cycloaddn. reaction was investigated. Thus, photolysis of cyclopentenone I (R = 4-cyanophenyl, R1 = 4-MeOC6H4) gave cycloaddn. products II (R = 4-cyanophenyl, R1 = 4-MeOC6H4, R2 = H) along with II (R = 4-cyanophenyl, R1 = H, R2 = 4-MeOC6H4), whereas, photolysis of I (R = Ph, R1 = 4-cyanophenyl) gave only II (R = Ph, R1 = H, R2 = 4-cyanophenyl). The results show that substituents have no effect on the regiochem. of the cycloaddn. reaction. .

4,5-Dihydroimidazo[1,2-a]pyrrolo[1,2,3-cd]benzimidazole derivatives, their preparation, and their therapeutic application as anticonvulsants, anxiolytics, and hypnotics

4,5-Dihydroimidazo[1,2-a]pyrrolo[1,2,3-cd]benzimidazole derivatives, their preparation, and their therapeutic application as anticonvulsants, anxiolytics, and hypnotics. George, Pascal; Sevrin, Mireille; Peynot, Michel Charles; Evanno, Yannick (Synthelabo S. A., Fr.). Fr. Demande FR 2741073 A1 16 May 1997, 26 pp. (French). (France). CODEN: FRXXBL. CLASS: ICM: C07D487-04. 20099-89-2 are also occured in this study. ICS: A61K031-415. ICI: C07D487-04, C07D233-88, C07D235-00. APPLICATION: FR 1995-13255 9 Nov 1995. DOCUMENT TYPE: Patent CA Section: 28 (Heterocyclic Compounds (More Than One Hetero Atom)) Section cross-reference(s): 1, 63 Title compds. I [Y = H, halo; X = cyano, CO2H, CO2Et, CONH2, and also (when Y = halo) X = H, halo, or alkyl; R = H, CH2CO2R1, CH2CONR2R3; R1, R2, R3 = H, alkyl] and their salts are disclosed. For instance, cyclocondensation of 5-fluoro-2,3-dihydro-1H-indol-7-amine with BrCN in aq. Na2CO3 gave the intermediate pyrrolobenzimidazole deriv. II. This compd.Chemical with cas number 20099-89-2 also plays role. underwent N-alkylation by BrCH2COPh, followed by cyclization of the product under Dean-Stark conditions, to give title compd. III. I bound to benzodiazepine receptors (w1 and w2) with IC50 of 1-1000 nM, and showed anticonvulsant, anxiolytic, and hypnotic activity in animal expts. ..