CAS No.20187-55-7,Acetic acid,2-[[1-(phenylmethyl)-1H-indazol-3-yl]oxy]- Suppliers

Detail of "20187-55-7"

CAS Number:

20187-55-7

Name:

Acetic acid,2-[[1-(phenylmethyl)-1H-indazol-3-yl]oxy]-

Superlist Name:

Bendazac

Molecular Structure:

Formula:

C₁₆H₁₄N₂O₃

Molecular Weight:

282.30

Synonyms:

Aceticacid, [(1-benzyl-1H-indazol-3-yl)oxy]- (8CI);Acetic acid,[[1-(phenylmethyl)-1H-indazol-3-yl]oxy]- (9CI);(1-Benzyl-3-indazolyl)oxyaceticacid;1-Benzylindazole-3-oxyacetic acid;AF 983;Bendazolic acid;Bindazac;Dogalina;Zildasac;Zildazac;

EINECS:

243-569-2

Density:

1.27 g/cm₃

Melting Point:

161-163 °C

Boiling Point:

508.2 °C at 760 mmHg

Flash Point:

261.1 °C

Solubility:

insoluble

Reference

Bendazac prevents cyanate binding to soluble lens proteins and cyanate-induced phase-separation opacities in vitro: a possible mechanism by which bendazac could delay cataract: Bendazac prevents cyanate binding to soluble lens proteins and cyanate-induced phase-separation opacities in vitro: a possible mechanism by which bendazac could delay cataract. Lewis, Bridget S.; Rixon, Ken C.; Harding, John J. (Nuffield Lab. Ophthalmol., Univ. Oxford, Oxford OX2 6AW, UK). Exp. Eye Res., 43(6), 973-9 (English) 1986. CODEN: EXERA6. ISSN: 0014-4835. DOCUMENT TYPE: Journal CA Section: 1 (Pharmacology) Bendazac [20187-55-7], a putative anticataract drug, decreased the binding of cyanate to lens proteins and prevented the cyanate-induced elevation of the phase-sepn. temp. in incubated rat lenses. Its major metabolite, 5-hydroxybendazac [84745-02-8], also inhibited the binding of cyanate to lens proteins even when present only during a preincubation period.In this experiment, several chemicals are used like 84745-02-8 and 420-05-3 The metabolite was more effective than the parent compd. .

Epidermal antihyperplastic effects of contact antiphlogistics: Epidermal antihyperplastic effects of contact antiphlogistics. Weirich, Erich G.; Longauer, Josef K.; Kirkwood, Alan H. (Pharm. Div., Ciba-Geigy Ltd., Basel, Switz.). Dermatologica, 156(1), 1-7 (English) 1978. CODEN: DERAAC. ISSN: 0011-9075. DOCUMENT TYPE: Journal CA Section: 1 (Pharmacodynamics) Section cross-reference(s): 2 The inhibitory effects of 6 contact antiphlogistics and 2 dermatocorticoids on hexadecane-induced hyperplasia of guniea pig skin were tested and compared. The substances were ranked in the following order of potency (percent inhibition of surface epithelial proliferation): acetylsalicylic acid [50-78-2] (7.9%), phenylbutazone [50-33-9] (12.5%), bufexamac [2438-72-4] (16.4%), bendazac [20187-55-7] (16.6%), oxyphenbutazone [129-20-4] (19.5%), indomethacin [53-86-1] (20.0%), hydrocortisone [50-23-7] (20.6%) and fluocinolone acetonide [67-73-2] (32.0%).

Detail of "20187-55-7"

Acetic acid,2-[[1-(phenylmethyl)-1H-indazol-3-yl]oxy]-

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CAS No.20187-55-7 Bendazac

CAS No.20187-55-7 Bendazac

CAS No.20187-55-7 Bendazac

CAS No.20187-55-7 Bendazac

CAS No.20187-55-7 Bendazac

Reference