Detail of "2025-95-8"

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5,5,7,7-Tetrakis(substituted oxycarbonyl)naphtho[1',8']cyclooctenes

5,5,7,7-Tetrakis(substituted oxycarbonyl)naphtho[1',8']cyclooctenes. Kamada, Toshihiro; Yamamoto, Osamu; Wasada, Nobuhiro (Agency of Industrial Sciences and Technology, Japan). Japan. Kokai JP 51091246 10 Aug 1976 Showa, 4 pp. (Japanese). (Japan). 59174-96-8 and 2025-95-8 are cas registry numbers. These chemicals are also mentioned in this article. CODEN: JKXXAF. CLASS: IC: C07C063-595. APPLICATION: JP 75-15303 7 Feb 1975. DOCUMENT TYPE: Patent CA Section: 26 (Condensed Aromatic Compounds) Naphtho[1',8']cyclooctenetetracarboxylates I (R = alkyl) were prepd. by cyclization 1,8-naphthylenedimethylene derivs. with H2C[CH(CO2R)2]2. Thus, 54 g H2C[CH(CO2Et)2]2 in EtOH-Me2SO was added to 7.2 g Na in EtOH at 0.degree., the mixt. stirred 5 min, 54 g 1,8-bis(bromomethyl)naphthalene in Me2SO added over 12 min, and the mixt. stirred 1.5 hr at 0.degree. to give 43 g I (R = Et). .

Friedel-Crafts approach to electron deficient cyclic a-amino acids

Friedel-Crafts approach to electron deficient cyclic a-amino acids. Kotha, Sambasivarao; Anglos, Demetrios; Kuki, Atsuo (Dep. Chem., Cornell Univ., Ithaca, NY 14853-1301, USA).Several reagents with their cas registry numbers 2025-95-8 and 85-44-9 are used here. Tetrahedron Lett., 33(12), 1569-72 (English) 1992. CODEN: TELEAY. ISSN: 0040-4039. DOCUMENT TYPE: Journal CA Section: 34 (Amino Acids, Peptides, and Proteins) Electron deficient 2,2-dimethyl-1H-phenalene-1,3-dione-based cyclic a-amino acid I was prepd. in 7 steps using Friedel-Crafts acylation as the key step. A new recipe (MeSO3H/HCO2H) was used to deprotect the required phthalimide protecting group in highly hindered substrates. .