Detail of "2032-75-9"

Reference

Process for fluorination of aryl alkyl ethers via treatment with chlorine and a radical initiator in dichlorobenzotrifluoride and then with hydrofluoric acid

Process for fluorination of aryl alkyl ethers via treatment with chlorine and a radical initiator in dichlorobenzotrifluoride and then with hydrofluoric acid. Biasetton, Silvia; Marinello, Franco (Miteni S.p.A., Italy). Eur. Pat. Appl. EP 1502908 A1 2 Feb 2005, 7 pp. DESIGNATED STATES: R: AT, BE, CH, DE, DK, ES, FR, GB, GR, IT, LI, LU, NL, SE, MC, PT, IE, SI, LT, LV, FI, RO, MK, CY, AL, TR, BG, CZ, EE, HU, PL, SK, HR. (English). (European Patent Organization). CODEN: EPXXDW. CLASS: ICM: C07C043-225. ICS: C07D317-46. APPLICATION: EP 2004-17173 21 Jul 2004. PRIORITY: IT 2003-MI1563 30 Jul 2003. DOCUMENT TYPE: Patent CA Section: 28 (Heterocyclic Compounds (More Than One Hetero Atom)) Section cross-reference(s): 25, 45 Title compds. 7782-50-5 and 2032-75-9 are cas registry numbers of chemicals which are used as reagents here. (I; R = F; R1 = H; or RR1 together = O; X = H, Cl, F), were prepd. by treatment of (II; R, R1 = H; or RR1 together = O; X = H, Cl, F) with gaseous Cl2 in the presence of a radical initiator in dichlorobenzotrifluoride followed by addn. of hydrofluoric acid and isolation of product. Thus, a refluxing soln. of 1,3-benzodioxole in 3,4-dichlorobenzotrifluoride was bubbled with Cl2 under UV irradn. to give a soln. of 2,2-dichloro-1,3-benzodioxole. The latter at 0-3° was treated portionwise with HF followed by heating to 50° to remove excess HF and purifn. by distn. to give 2,2-difluoro-1,3-benzodioxole in 83% yield. .