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20354-26-1

Basic Information
CAS No.: 20354-26-1
Name: METHAZOLE
Article Data: 8
Molecular Structure:
Molecular Structure of 20354-26-1 (METHAZOLE)
Formula: C9H6 Cl2 N2 O3
Molecular Weight: 261.064
Synonyms: 2-(3,4-Dichlorophenyl)-4-methyl-1,2,4-oxadiazolidine-3,5-dione;Bioxone; Chlormethazole; Metazol; Metazole; Methazole; Mezopur; Probe; Probe75; Tunic; Tunic (pesticide); VCS 438
EINECS: 243-761-6
Density: 1.602 g/cm3
Melting Point: 123-124oC
Boiling Point: 348.7 °C at 760 mmHg
Flash Point: 164.7 °C
Solubility: 1.5mg/L(25 oC)
Hazard Symbols: Xn,N
Risk Codes: 21/22-36/38-51/53
Safety: Moderately toxic by ingestion. When heated to decomposition it emits very toxic fumes of Cl and NOx.
PSA: 57.14000
LogP: 1.43600
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Chemistry

Chemistry informtion about Methazole (CAS NO.20354-26-1) is:
IUPAC Name: 2-(3,4-Dichlorophenyl)-4-Methyl-1,2,4-Oxadiazolidine-3,5-Dione
Synonyms: 2-(3,4-Dichlorophenyl)-4-Methyl-1,2,4-Oxadiazolidine-3,5-Dione ; Methazole ; 1,2,4-Oxadiazolidine-3,5-Dione, 2-(3,4-Dichlorophenyl)-4-Methyl- ; 2-(3,4-Dichlorophenyl)-4-Methyl-1,2,4-Oxadiazolidinedione ; 4-Oxadiazolidine-3,5-Dione,2-(3,4-Dichlorophenyl)-4-Methyl-2 ; Bioxone ; Chlormethazole ; Metazol
MF: C9H6Cl2N2O3
MW: 261.06
EINECS: 243-761-6 
Density: 1.602 g/cm3
Flash Point: 164.7 °C
Boiling Point: 348.7 °C at 760 mmHg
Vapour Pressure: 4.94E-05 mmHg at 25°C
Enthalpy of Vaporization: 59.31 kJ/mol
Storage temp.: 0-6°C
Following is the molecular structure of Methazole (CAS NO.20354-26-1) is:

Uses

 Methazole (CAS NO.20354-26-1) is used in a variety of upland control broadleaf weeds and some grassy weeds.

Toxicity Data With Reference

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal 600mg/kg (600mg/kg)   Journal of Agricultural and Food Chemistry. Vol. 21, Pg. 386, 1973.
rabbit LD50 skin 12500mg/kg (12500mg/kg)   Farm Chemicals Handbook. Vol. -, Pg. C248, 1991.
rat LC50 inhalation > 200gm/m3/4H (200000mg/m3)   Pesticide Manual. Vol. 9, Pg. 565, 1991.
rat LD50 oral 777mg/kg (777mg/kg)   Fundamental and Applied Toxicology. Vol. 7, Pg. 299, 1986.
rat LD50 skin 10200mg/kg (10200mg/kg)   "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986Vol. -, Pg. 890, 1986.

Safety Profile

Moderately toxic by ingestion. When heated to decomposition it emits very toxic fumes of Cl and NOx
Hazard Codes:
HarmfulXn
DangerousN
Risk Statements:
R21/22:Harmful in contact with skin and if swallowed. 
R36/38:Irritating to eyes and skin. 
R51/53:Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment.
Safety Statements:
S36/37:Wear suitable protective clothing and gloves. 
S61:Avoid release to the environment. Refer to special instructions / safety data sheets.

Specification

Methazole (CAS NO.20354-26-1) is a colorless crystals to light tan solid and it is non corrosive. It hydrolyzed by strong acids and bases. Also it is a herbicide in the family of herbicides known as oxadiazolones.