Detail of "2066-93-5"

Reference

Inhibition of urease by miscellaneous ions and compounds

Inhibition of urease by miscellaneous ions and compounds. Implications for the therapy of infection-induced urolithiasis. Burr, R. G. (Natl. Spinal Injuries Cent., Stoke Mandeville Hosp., Aylesbury, Engl.). Invest. Urol., 15(2), 180-2 (English) 1977. CODEN: INURAQ. DOCUMENT TYPE: Journal CA Section: 1 (Pharmacodynamics) One hundred forty-eight drugs and other org. and inorg. substances were screened for their ability to inhibit the enzyme urease [9002-13-5] in an in vitro system modeled on infected urine. The reported urease-inhibiting properties of ascorbic acid, tetracyclines, and sulfanilamide were not confirmed. At least 50 % inhibition was obsd.There are some reagents like 12002-50-5 is used in this study. in the presence of kanamycin [8063-07-8], hydroxyguanidine [13115-21-4], benzoquinone [106-51-4], 1,2-naphtoquinone-4-sulfonate [2066-93-5], chloramine-T [127-65-1] N-bromoacetamide [79-15-2], Cu, Hg, and F. It is, however, unlikely that therapeutically effective concns. can be attained in urine without giving dosages likely to result in toxic effects. Hydroxyurea [127-07-1], at the dose level used in cytotoxic therapy, may be expected to produce effective inhibition of bacterial urease in the urinary tract, providing renal function is unimpaired and providing urinary vol. does not exceed 1 L/24 h. Acetohydroxamic acid [546-88-3] is potentially the most useful drug for the treatment of infection-induced urinary stone disease available at present. .

Determination of lincomycin levels in ambient air

Determination of lincomycin levels in ambient air.Some chemicals with cas registry numbers like 2066-93-5 and 154-21-2 are also used. Churagulova, N. K. (All-Union Res. Inst. Antibiot., Moscow, USSR). Antibiot. Med. Biotekhnol., 32(3), 220-3 (Russian) 1987. CODEN: AMBIEH. DOCUMENT TYPE: Journal CA Section: 59 (Air Pollution and Industrial Hygiene) Section cross-reference(s): 16, 18 The detn. of lincomycin (I) [154-21-2] in the workplace air in antibiotic manufg. plants is based on the formation of a molybdenum blue heteropoly complex in the reaction of I with Folin's reagent [2066-93-5] and photometric measurement at 660 nm. The upper detection limit is 0.25 mg/m3. The presence of sugar and starch in the air does not interfere with the detn. The method is suitable for hygienic monitoring of workplace exposure to I. .