Detail of "2068-83-9"

Reference

b-Hydroxyisobutyric acid by fermentation

b-Hydroxyisobutyric acid by fermentation. (Mitsubishi Rayon Co., Ltd., Japan). Jpn. Kokai Tokkyo Koho JP 59118092 A2 7 Jul 1984 Showa, 4 pp. (Japanese). (Japan). CODEN: JKXXAF. CLASS: IC: C12P007-42; C12P007-52. ICI: C12P007-52, C12R001-72. APPLICATION: JP 82-225000 23 Dec 1982. DOCUMENT TYPE: Patent CA Section: 16 (Fermentation and Bioindustrial Chemistry) Candida ohtakeensis Is cultured in the presence of methacrylic acid (I) [79-41-4] or isobutyric acid [79-31-2] to give b-hydroxyisobutyric acid (II) [2068-83-9]. Thus, a preculture of C. ohtakeensis (MR-1023) was cultured in a liq. medium contg. glucose, yeast ext., (NH4)2SO4, K2HPO4, MgSO4, I (Na salt), and defoaming agent at 30° with shaking and aeration. The fermn. was continued after addn. of I (Na salt), keeping the pH at 8.0 throughout. The culture was centrifuged to remove the mycelia, acidified, and extd. with AcOEt to give 29.5 g. II.

Interorgan metabolism of valine

Interorgan metabolism of valine. Brosnan, M. E.; Letto, J. (Dep. Biochem., Mem. Univ. Newfoundland, St. John's, NF A1B 3X9, Can.). Amino Acids, 1(1), 29-35 (English) 1991. CODEN: AACIE6. DOCUMENT TYPE: Journal CA Section: 13 (Mammalian Biochemistry) Oxidn. of the branched-chain amino acids, leucine, isoleucine, and valine, is thought to occur primarily in muscle. Theor., however, it is possible for valine carbon to be converted to glucose, a process which only occurs in liver and kidney. Evidence is provided that valine is oxidized to b-hydroxyisobutyrate in muscle, and that this this intermediate is released from muscle and taken up by liver and kidney for subsequent conversion to glucose, thus conserving the gluconeogenic potential of valine.Except for chemicals metioned above, 2068-83-9 and 72-18-4 are also used. .