Reference

TLC-profile analysis of Bupleurum

TLC-profile analysis of Bupleurum. Lin, Mingmei; Luo, Yan (Beijing Inst. Clin. Pharm., Beijing, Peop. Rep. China). Yaowu Fenxi Zazhi, 7(1), 13-16 (Chinese) 1987. CODEN: YFZADL. ISSN: 0254-1793. DOCUMENT TYPE: Journal CA Section: 63 (Pharmaceuticals) Section cross-reference(s): 11, 62 The essential oils and n-hexane ext. of roots of Bupleurum chinense, B. scorzonerifolium, B. longiradiatum, B. bicaule, and B. sibiricum were sepd. by TLC., using petroleum ether-AcOEt (9:1) and CHCl3-PhMe (6:1), resp., as developing agents and scanning at ls = 525 and 255 nm, resp. 20736-09-8 and 20736-08-7 which are cas registry numbers of chemicals are mentioned., and lR = 795 and 400 nm, resp. Saikosaponin a [20736-09-8], c [20736-08-7], and d [20874-52-6] in the MeOH ext. of these roots were sepd. by TLC, using AcOEt-EtOH-H2O (8:2:1) as developing agent and fluorometric scanning at 370 (for excitation) and 500 nm (for emission). These different kinds of Bupleurum can be identified by profile anal. of their chromatograms. .

Pharmacological studies of preparations containing bupleuri radix

Pharmacological studies of preparations containing bupleuri radix. (V). Effects of adrenalectomy on the pharmacological actions of saikosaponin D. Abe, Hiroko; Sakaguchi, Machiko; Arichi, Shigeru (Res. Inst. Orient. Med., Kinki Univ., Osaka, Japan). Kinki Daigaku Igaku Zasshi, 8(4), 379-83 (Japanese) 1983. CODEN: KDIZDD. ISSN: 0385-8367. DOCUMENT TYPE: Journal CA Section: 1 (Pharmacology) The antigranulomatous action of saikosaponin D (I) [20874-52-6] (0.3 mg/kg ′ 4 days) was not influenced by adrenalectomy in rats. The rate of lowering of hepatic NADPH-cytochrome c reductase activity by saikosaponin D was slightly decreased by adrenalectomy. The actions lowering the serum levels of cholesterol and triglycerides by saikosaponin D were not obsd. in the adrenalectomized rats. Thus, the antigranulomatous action is not mediated by the adrenal gland, but the action of saikosaponin D on lipid metab. depends on the adrenal gland.