Detail of "2088-71-3"

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Synchronization of preovulatory LH surges after PGF2

Synchronization of preovulatory LH surges after PGF2.alpha. in beef cattle: the effects of D-Ala-GnRH and testosterone benzoate.Several substances are used for example 2088-71-3 and 38562-01-5 which are their cas registry numbers. Fernandez-Limia, O.; Murphy, B. D.; Manns, J. G. (Dep. Fisiol., Cent. Nac. Salud Anim., Havana, Cuba). Theriogenology, 7(2), 73-81 (English) 1977. CODEN: THGNBO. DOCUMENT TYPE: Journal CA Section: 2 (Hormone Pharmacology) Three successive periods of estrus were induced by PGF2.alpha.-THAM salt (I THAM salt) [38562-01-5] administration in beef cows and heifers. The magnitude, duration and timing of preovulation LH [9002-67-9] surges were compared in animals subjected to each of the following treatments during 1 of the periods of estrus following I injection: no treatment, 50 .mu.g AY25205 [52435-06-0] i.m. at 64 h, or 3 mg testosterone benzoate(II) [2088-71-3] i.m. at 48 h. Spontaneous LH surges, 15-40 ng/mL in magnitude and 8-12 h in duration occurred between 60 and 104 h after I. II suppressed and appeared to delay LH surges in 2 of 3 trials. AY25205 induced preovulatory surges which were considerably greater in magnitude but slightly shorter in duration than spontaneous surges. Apparently, AY25205 administered 64 h after the luteolytic dose of I is an effective means of synchronization of preovulatory LH surges. Further, this treatment may be a valuable aid in improving fertility to a single insemination in I-synchronized beef cows. .