Detail of "209615-79-2"

CAS Number:
209615-79-2
Name:
L-Leucine,L-isoleucyl-L-prolyl-L-isoleucyl-L-tyrosyl-L-a-glutamyl-L-lysyl-L-lysyl-L-tyrosylglycyl-L-glutaminyl-L-valyl-L-prolyl-L-methionyl-L-cysteinyl-L-a-aspartyl-L-alanylglycyl-L-a-glutamyl-L-glutaminyl-L-cysteinyl-L-alanyl-L-valyl-L-arginyl-L-lysylglycyl-L-alanyl-L-arginyl-L-isoleucylglycyl-L-lysyl-L-leucyl-L-cysteinyl-L-a-aspartyl-L-cysteinyl-L-prolyl-L-arginylglycyl-L-threonyl-L-seryl-L-cysteinyl-L-asparaginyl-L-seryl-L-phenylalanyl-L-leucyl-L-leucyl-L-lysyl-L-cysteinyl-,cyclic (14®32),(20®40)
Formula:
C226H367 N65 O65 S7
Melting Point:
153-156ºC
Appearance:
White or off-white power

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Supplier:EMD Biosciences, Inc. [ United States]

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CART (55-102) (RAT)

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CART (cocaine- and amphetamine-regulated transcript) peptide receptors: Specific binding in AtT20 cells: CART (cocaine- and amphetamine-regulated transcript) peptide receptors: Specific binding in AtT20 cells. Vicentic, Aleksandra; Lakatos, Anita; Kuhar, Michael J. (Neuroscience Division, Yerkes National Primate Research Center of Emory University, Atlanta, GA 30033, USA). European Journal of Pharmacology, 528(1-3), 188-189 (English) 2005 Elsevier B.V. CODEN: EJPHAZ. ISSN: 0014-2999. DOCUMENT TYPE: Journal CA Section: 2 (Mammalian Hormones) Section cross-reference(s): 13 Given previous evidence for CART (cocaine- and amphetamine-regulated transcript) signaling in AtT20 cells, the binding of [125I]-CART61-102 was characterized in these cells.In this article, certain chemicals are used. Some of their cas registry numbers are 209615-79-2 and 209615-75-8 The binding was specific, saturable, dependent on time, pH, temp. and protein concn., with a B max of 101.4±8.8 fmol/mg protein and a K d of 21.9±8.0 pM. Only active CART55-102, but not other peptides or drugs, inhibited the [125I]-CART61-102 binding. These data are the first demonstration of specific receptor binding for CART peptides. .