Products Categories
CAS No.: | 2104-19-0 | ||||
---|---|---|---|---|---|
Name: | AZELAIC ACID MONOMETHYL ESTER | ||||
Article Data: | 50 | ||||
Molecular Structure: | |||||
Formula: | C10H18 O4 | ||||
Molecular Weight: | 202.251 | ||||
Synonyms: | Azelaicacid, methyl ester (6CI,7CI); Azelaic acid, monomethyl ester (8CI); Nonanedioicacid, monomethyl ester (9CI); 8-Carbomethoxyoctanoic acid;9-Methoxy-9-oxononanoic acid; Methyl 8-carboxyoctanoate; Methyl hydrogenazelate; Monomethyl azelaate; Monomethyl azelate; Monomethyl nonanedioate; NSC60226 | ||||
Density: | 1.054g/cm3 | ||||
Melting Point: |
22-24 °C(lit.) |
||||
Boiling Point: |
159-160 °C3 mm Hg(lit.) |
||||
Flash Point: | 111.7°C | ||||
Solubility: | Not miscible in water. | ||||
Appearance: | Low Melting Solid | ||||
Safety: |
|
||||
PSA: | 63.60000 | ||||
LogP: | 1.97470 |
Conditions | Yield |
---|---|
With porcine liver esterase; sodium hydroxide; phosphate buffer for 6h; | 97% |
With barium dihydroxide In methanol 4 d, - 10 deg C; 10 h, RT; | 85% |
With barium dihydroxide In methanol Ambient temperature; | 84% |
Conditions | Yield |
---|---|
With sulfuric acid | 92% |
dimethyl 8,8'-(oxirane-2,3-diyl)dioctanoate
azelaic monomethyl ester
Conditions | Yield |
---|---|
With dihydrogen peroxide; 3C8H17NO3S*3H(1+)*Mo12O40P(3-) In water at 85℃; for 8h; Temperature; | 91.27% |
methyl 9-[(tetrahydro-2H-pyran-2-yl)oxy]nonanoate
azelaic monomethyl ester
Conditions | Yield |
---|---|
With jones reagent In acetone at 0℃; | 79% |
Conditions | Yield |
---|---|
With aluminum oxide at 25℃; for 48h; Green chemistry; chemoselective reaction; | A 9% B 73% |
With sulfuric acid | |
With sulfuric acid at 120℃; for 3h; |
Conditions | Yield |
---|---|
With potassium permanganate; sodium periodate; potassium carbonate In water; tert-butyl alcohol for 66h; | A 64% B 40% |
With potassium permanganate; sodium periodate; potassium carbonate In water; tert-butyl alcohol for 66h; | A 62% B 40% |
With potassium permanganate; silica gel Yield given. Yields of byproduct given. Title compound not separated from byproducts; |
Conditions | Yield |
---|---|
With methanol; potassium hydroxide; acetonitrile In diethyl ether at 0℃; for 50h; | 62% |
Conditions | Yield |
---|---|
With DOWEX 50W-X2 In Petroleum ether for 4h; Heating; | 60% |
stearolic acid methyl ester
A
azelaic monomethyl ester
B
9,10-dioxooctadecanoic acid methyl ester
C
methyl 11-oxo-10-nitrooctadecanoate
D
methyl 10-oxo-11-nitrooctadecanoate
Conditions | Yield |
---|---|
With nitric acid; sodium nitrite In acetic acid | A 12% B 37% C 39% D n/a |
With nitric acid; sodium nitrite In acetic acid other acetylenic fatty acid ester; | A 12% B 37% C 39% D n/a |