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21172-28-1

Basic Information
CAS No.: 21172-28-1
Name: 2-Amino-1-[3-(trifluoromethyl)phenyl]ethanol
Article Data: 7
Molecular Structure:
Molecular Structure of 21172-28-1 (2-Amino-1-[3-(trifluoromethyl)phenyl]ethanol)
Formula: C9H10 F3 N O
Molecular Weight: 205.18
Synonyms: Benzylalcohol, a-(aminomethyl)-m-(trifluoromethyl)-(8CI); 2-Amino-1-[3-(trifluoromethyl)phenyl]ethanol
Density: 1.301g/cm3
Boiling Point: 277.9°C at 760 mmHg
Flash Point: 121.9°C
Safety: Poison by intraperitoneal route. Moderately toxic by ingestion. When heated to decomposition it emits very toxic fumes of F and NOx.
PSA: 46.25000
LogP: 2.39780
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Chemistry

IUPAC Name: 2-Amino-1-[3-(trifluoromethyl)phenyl]ethanol
Synonyms of α-Aminomethyl-m-trifluoromethyl benzyl alcohol (CAS NO.21172-28-1): alpha-Aminomethyl-m-trifluoromethylbenzyl alcohol ; Benzyl alcohol, alpha-aminomethyl-m-trifluoromethyl-
Product Categories: API intermediates
CAS NO: 21172-28-1
Molecular Formula: C9H10F3NO
Molecular Weight : 205.177010 g/mol
Molecular Structure:
H bond acceptors: 2
H bond donors: 3
Freely Rotating Bonds: 4
Polar Surface Area: 12.47 Å2
Index of Refraction: 1.493
Molar Refractivity: 45.85 cm3
Molar Volume: 157.6 cm3
Surface Tension: 35.7 dyne/cm
Density: 1.301 g/cm3
Flash Point: 121.9 °C
Enthalpy of Vaporization: 54.55 kJ/mol
Boiling Point: 277.9 °C at 760 mmHg
Vapour Pressure: 0.00211 mmHg at 25°C

Toxicity Data With Reference

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal 226mg/kg (226mg/kg)   "International Symposium on Amphetamines and Related Compounds, Proceedings, Mario Negri Institute for Pharmacological Research, Milan, 1969," Costa, E., and S. Garattini, eds., New York, Raven Press, 1970Vol. -, Pg. 21, 1970.

Safety Profile

Poison by intraperitoneal route. Moderately toxic by ingestion. When α-Aminomethyl-m-trifluoromethyl benzyl alcohol (CAS NO.21172-28-1) is heated to decomposition, it emits very toxic fumes of F and NOx.