Detail of "2134-48-7"

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The effect of b-aminoproprionitrile on the lingual artery and aorta of the rat: a light microscopic study

The effect of b-aminoproprionitrile on the lingual artery and aorta of the rat: a light microscopic study. Baden, E.; Bouissou, H.; Pieraggi, M. T.; Julian, M. (Sch. Dent., Fairleigh Dickinson Univ., Hackensack, NJ, USA). J. Biol. Buccale, 10(3), 227-35 (English) 1982.Several reagents such as 2134-48-7 is used here. CODEN: JBBUA3. ISSN: 0301-3952. DOCUMENT TYPE: Journal CA Section: 4 (Toxicology) The effects of chronic toxicity of b-aminoproprionitrile (BAPN) [2134-48-7] on the lingual artery and aorta of the rat were compared. Three-wk-old weanling male rats were given 1 g/kg/day (for 5 days weekly) of a 40% satd. soln. of BAPN fumarate by intragastric tube. The animals were divided into 4 groups and sacrificed after 1, 6, and 9 wk, resp. Cross-sections of the lingual artery and aorta stained with hematoxylin-erythrosin-safranine, alcian blue, Masson's trichrome, and Verhoeff's Fe hematoxylin were studied. BAPN had no effect on the lingual artery. Early changes were seen in the aorta at 6 wk. Characteristic lesions were found at 9 wk involving the elastic tissue, myocytes, and ground substance. The elastic lamellae were thinner, lost their normal orientation, and became swollen and finally fragmented. The myocytes of the media changed orientation and migrated into the intima. The proteoglycans increased and fibrosis predominated at the end stage. Failure to induce lesions in the lingual artery may be explained by early structural maturation and a low metabolic turnover rate in muscular arteries, decreased exposure to or greater protection from mech. stress. .

Ethyl carbethoxyformimidate in heterocyclic chemistry

Ethyl carbethoxyformimidate in heterocyclic chemistry. Gomez, E.; Avendano, C.; McKillop, A. (Fac. Farm.Some commonly used reagents like 16750-42-8 is used in this experiment., Univ. Complutense Madrid, Madrid, Spain). Tetrahedron, 42(10), 2625-34 (English) 1986. CODEN: TETRAB. ISSN: 0040-4020. DOCUMENT TYPE: Journal CA Section: 28 (Heterocyclic Compounds (More Than One Hetero Atom)) Section cross-reference(s): 23 The use of EtO2CC(NH)OEt (I) in the prepn. of a variety of heterocycles is reported. Thus, I was treated with EtO2CCH(NH2)CN in Et2O for 24 h at room temp. to give 51.4 aminoimidazoledicarboxylate II. Likewise, treating I with 2-H2NC6H4CONH2 in refluxing EtOH gave 42% dihydrooxoquinazolinecarboxylate III. .