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Detail of "21736-83-4"

  • MSDS Download
  • CAS Number:
  • 21736-83-4
  • Name:

  • 4H-Pyrano[2,3-b][1,4]benzodioxin-4-one,decahydro-4a,7,9-trihydroxy-2-methyl-6,8-bis(methylamino)-, hydrochloride(1:2), (2R,4aR,5aR,6S,7S,8R,9S,9aR,10aS)-

  • Superlist Name:
  • Spectinomycin dihydrochloride
  • Molecular Structure:
  • Formula:
  • C14H26Cl2N2O7
  • Molecular Weight:
  • 405.32
  • Synonyms:
  • 4H-Pyrano[2,3-b][1,4]benzodioxin-4-one,decahydro-4a,7,9-trihydroxy-2-methyl-6,8-bis(methylamino)-, dihydrochloride,(2R,4aR,5aR,6S,7S,8R,9S,9aR,10aS)- (9CI);(+)-Spectinomycin dihydrochloride;NSC 248616;Spectinomycindihydrochloride;Stanilo;sectinomycin HCl;
  • EINECS:
  • 244-554-3
  • Melting Point:
  • 194 °C
  • Boiling Point:
  • 583.1 °C at 760 mmHg
  • Flash Point:
  • 306.4 °C
  • Solubility:
  • water: 50 mg/mL, clear, faintly yellow
  • Appearance:
  • white powder
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CAS No.21736-83-4 Spectinomycin dihydrochlorideCompetitive Product

Assay:Assay93.0%-1...  Appearance:white or alm...  Package:4kg/tin.2tin...

Spectinomycin Hydrochloride Sterile spcification:EP5 Packing:4kg/tin,2tins/carton Description:white or almost white powder,slightly hygroscopic

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Reference

Study of the antibiotic sensitivity of gonococcus strains isolated in Djibouti
Study of the antibiotic sensitivity of gonococcus strains isolated in Djibouti. Morvan, D.; Carteron, B. (Hop. Armees, Fr.). Med. Trop. (Marseille), 37(1), 93, 95-6 (French) 1977. CODEN: METRA2. DOCUMENT TYPE: Journal CA Section: 1 (Pharmacodynamics) Section cross-reference(s): 3 All Neisseria gonorrhoeae strains examd. were sensitive to tetracycline [60-54-8], chloramphenicol [56-75-7], and pristinamycin [11006-76-1]. Sixty percent and 45% of the strains were resistant to streptomycin [57-92-1] and Bactrim [8064-90-2], resp. In clin. studies, spectinomycin-2HCl [21736-83-4] was therapeutically effective against all 30 cases of gonorrhea treated.
Crystal structure of spectinomycin dihydrochloride
Crystal structure of spectinomycin dihydrochloride. Bao, Ying; Wang, Jing-kang; Huang, Xiang-rong; Zi, Zhen; Wang, Hong-bin (College of Chemical Eng. and Technology, Tianjin Univ., Tianjin 300072, Peop. Rep. China). Huadong Ligong Daxue Xuebao, 29(4), 336-340 (Chinese) 2003 Huadong Ligong Daxue Xuebao Bianjibu. CODEN: HLIXEV. ISSN: 1006-3080. DOCUMENT TYPE: Journal CA Section: 75 (Crystallography and Liquid Crystals) Section cross-reference(s): 1, 63 Single crystal of spectinomycin dihydrochloride was cultivated by natural cooling method according to its characteristic of soly. It is demonstrated by x-ray diffraction that the crystal obtained whether by cooling or by diln. belongs. to orthorhombic crystal system, P212121 space group. 21736-83-4 is also in the experiment. Crystallog. data are given. The mol. exists as the ketone hydrate, not in the carbonyl form. The H bonds formed along axis b are stronger than those along c and a. This is the possible reason why crystal of spectinomycin dihydrochloride pentahydrate grows more rapidly along the b direction, resulting in stick shape. .
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