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Detail of "2197-63-9"

  • CAS Number:
  • 2197-63-9
  • Name:
  • 1-Hexadecanol,1,1'-(hydrogen phosphate)

  • Molecular Structure:
  • Formula:
  • C32H67O4P
  • Molecular Weight:
  • 546.85
  • Synonyms:
  • 1-Hexadecanol,hydrogen phosphate (8CI,9CI);Bis(hexadecyl) phosphate;DAP 60H;Di(hexadecyl)monohydrogen phosphate;Di-n-hexadecyl phosphate;Dicetyl hydrogen phosphate;Dicetyl phosphate;Dihexadecyl hydrogen phosphate;Dihexadecyl phosphate;NSC12429;Phosphoric acid dihexadecyl ester;
  • EINECS:
  • 218-594-7
  • Density:
  • 0.925 g/cm3
  • Melting Point:
  • 74-75 °C(lit.)
  • Boiling Point:
  • 600.4 °C at 760 mmHg
  • Flash Point:
  • 316.9 °C

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CAS No.2197-63-9 1-Hexadecanol,1,1'-(hydrogen phosphate)

DICETYL PHOSPHATE

Supplier:Nacalai Tesque, Inc. [ Japan]

610Integral
610

Tel:81 75 251 1723 81-75-251-1730

Address:Nijo Karasuma, Nakagyo-ku Kyoto 604-0855 Japan

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CAS No.2197-63-9 1-Hexadecanol,1,1'-(hydrogen phosphate)

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Supplier:Croda Inc [ United States]

253Integral
253

Tel:732-417-0800

Address:300-A Columbus Circle Edison, NJ 08837

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Reference

Cytosine arabinoside formulation
Cytosine arabinoside formulation. Sakurai, Tetsuo; Tsukagoshi, Shigeru; Kataoka, Takeyuki; Kobayashi, Tomoo (Zaidan Hojin Gan Kenkyukai, Japan). Japan. Kokai JP 52114015 24 Sep 1977 Showa, 4 pp. (Japanese). (Japan). CODEN: JKXXAF. CLASS: IC: A61K009-20. APPLICATION: JP 76-19594 24 Feb 1976. DOCUMENT TYPE: Patent CA Section: 63 (Pharmaceuticals) The mixt. of the following 3 substances, (1) sphingomyelins or lecithins, (2) cholesterol [57-88-5], and (3) stearylamine-HCl [1838-08-0] or dicetyl phosphate [2197-63-9], is used to encapsulate cytosine arabinoside (I) [147-94-4]. This product has a long-lasting antitumor activity. For example, a mixt. of sphingomyelins 20, cholesterol 15, and stearylamine-HCl 2 mmol was used to encapsulate 7.3 mg of I. Three of 5 mice with leukemia L-1210 cells injected i.p. with encapsulated I (50 mg/kg) survived 60 days, whereas all 5 controls that received noncapsulated I did not survive.
Liposomes from glycolipids
Liposomes from glycolipids. (Saida, Hiroshi, Japan). Jpn. Kokai Tokkyo Koho JP 59106423 A2 20 Jun 1984 Showa, 2 pp. (Japanese). (Japan). CODEN: JKXXAF. CLASS: IC: A61K047-00. ICA: A61K009-10; C07H015-00. APPLICATION: JP 82-214893 8 Dec 1982. DOCUMENT TYPE: Patent CA Section: 63 (Pharmaceuticals) Liposomes are prepd. from synthetic glycolipids in which alkyl groups are bound to sugars, and these liposomes may be used as drug carriers. Thus, glycolipids were prepd. by binding myristyl, cetyl, and stearyl groups to D-glucose [50-99-7]. Liposomes were prepd. from the glycolipids. Cholesterol [57-88-5] was added to increase the flexibility of the liposome membrane, and dicetyl phosphate [2197-63-9] was added to prevent the liposome aggregation.
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