Detail of "2202-17-7"

CAS Number:
2202-17-7
Name:
Isoquinoline,1,2,3,4-tetrahydro-6,7-dimethoxy-1-[[4-[2-methoxy-5-[[(1R)-1,2,3,4-tetrahydro-6,7-dimethoxy-2-methyl-1-isoquinolinyl]methyl]phenoxy]phenyl]methyl]-2-methyl-,(1R)-
Superlist Name:
O-Methyldauricine
Molecular Structure:
Formula:
C₃₉H₄₆N₂O₆
Molecular Weight:
638.79
Synonyms:
Dauricine,O-methyl- (6CI,7CI,8CI);Isoquinoline,1,2,3,4-tetrahydro-6,7-dimethoxy-1-[[4-[2-methoxy-5-[(1,2,3,4-tetrahydro-6,7-dimethoxy-2-methyl-1-isoquinolinyl)methyl]phenoxy]phenyl]methyl]-2-methyl-,[R-(R*,R*)]-;(-)-O-Methyldauricine;O,O-Dimethylcuspidaline;O,O-Dimethyldauricinoline;O-Methyldauricine;
Density:
1.156g/cm³
Boiling Point:
717.6 °C at 760 mmHg
Flash Point:
173.2 °C

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Pharmacokinetic studies on tritiated O-methyldauricine: Pharmacokinetic studies on tritiated O-methyldauricine. Dai, Zhongshun; Li, Zhimin; Li, Jian; Hu, Chongjia (Fac. Premed. Preclin. Sci., Wuhan Med. Coll., Wuhan, Peop. Rep. China). Wuhan Yixueyuan Xuebao, 13(5), 352-4 (Chinese) 1984. CODEN: WHYHAQ. ISSN: 0510-9752. DOCUMENT TYPE: Journal CA Section: 1 (Pharmacology) The pharmacokinetics of 3H-labeled O-methyldauricine [2202-17-7] were studied in rats. The logarithm of drug concn. in plasma vs. time after oral administration fitted a 2-compartment open model with 1st-order elimination. The pharmacokinetic parameters were as follows: distribution half-life 0.48 h, elimination half-life 9.43 h, absorption half-life 0.2 h, elimination rate const. 0.132/h, pcs. transfer rate const. 0.582/h, converse transfer rate const. 0.799/h, peak concn. 0.461 mg/mL, time of peak concn. 0.61 h. The radioactivities excreted in feces and urine accounted for 21.59 and 1.97%, resp.