Reference

Effect of hydrocortisone on the size of the synaptic endings of spinal cord motor neurons

Effect of hydrocortisone on the size of the synaptic endings of spinal cord motor neurons. Emel'yanov, N. A.; Korneeva, T. E. (Inst. Fiziol. im. Pavlova, Leningrad, USSR). Dokl. Akad. Nauk SSSR, 233(2), 506-8 [Physiol.] (Russian) 1977. CODEN: DANKAS. DOCUMENT TYPE: Journal CA Section: 2 (Hormone Pharmacology) Hydrocortisone hemisuccinate (I hemisuccinate) [2203-97-6] (1 mg) injected into frogs (Rana temporaria) prevented the increase in the diam. of the synaptic endings of spinal cord motoneurons caused by stimulation.

Pharmacological effector action on hematocrit and lactate dehydrogenase activity during experimental ischemic shock

Pharmacological effector action on hematocrit and lactate dehydrogenase activity during experimental ischemic shock. Jonadet, M.; Bastide, P. (Lab. Chim. Biol. Pharmacodyn., CNRS, Clermont-Ferrand, Fr.). Pathol.-Biol., 25(3), 147-51 (French) 1977. CODEN: PTBIAN. DOCUMENT TYPE: Journal CA Section: 2 (Hormone Pharmacology) When ischemic shock was induced in rats the hematocrit first increased with a peak at 18 h and then decreased to the basal level by 96 h. Plasma lactate dehydrogenase (LDH) [9001-60-9] activity increased rapidly reaching a peak at 18 h and then decreasing to slightly above basal levels at 164 h. The muscle LDH, however, decreased drastically by 18 h with a recovery to normal by 164 h. Dexamethasone phosphate [312-93-6] given after 3 and 18 h normalized the hematocrit values. Hydrocortisone hemisuccinate [2203-97-6] and aprotinin [9039-77-4] were somewhat less effective. The response of LDH in plasma and muscle to these antishock compds. was somewhat less. Dexamethasone phosphate was the best antishock treatment.