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Detail of "23541-50-6"

  • MSDS Download
  • CAS Number:
  • 23541-50-6
  • Name:

  • 5,12-Naphthacenedione,8-acetyl-10-[(3-amino-2,3,6-trideoxy-a-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-,hydrochloride (1:1), (8S,10S)-

  • Superlist Name:
  • Daunorubicin hydrochloride
  • Molecular Structure:
  • Formula:
  • C27H29NO10.HCl
  • Molecular Weight:
  • 564.03
  • Deleted CAS:
  • 52471-42-8
  • Synonyms:
  • 5,12-Naphthacenedione,8-acetyl-10-[(3-amino-2,3,6-trideoxy-a-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-,hydrochloride, (8S,10S)- (9CI);Cerubidine;Daunoblastin;Daunomycin chlorohydrate;NDC0082-4155;Ondena;RP 13057 hydrochloride;Rubidomycin hydrochloride;
  • EINECS:
  • 245-723-4
  • Density:
  • 1.554 g/cm3
  • Melting Point:
  • 190°C (dec)
  • Boiling Point:
  • 770 °C at 760 mmHg
  • Flash Point:
  • 419.5 °C
  • Appearance:
  • dark red crystals
  • Hazard Symbols:
  • HarmfulXn,IrritantXi
  • Risk Codes:
  • 22-40-42/43-36/37/38-20/21/22
  • Safety:
  • 22-36/37-45-37/39-36-26 Details
  • Transport Information:
  • UN 2811 6.1/PG 3
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CAS No.23541-50-6 Daunorubicin hydrochlorideCompetitive Product

Daunorubicin hydrochloride Identification Name Daunorubicin hydrochloride Synonyms (8S-cis)-8-Acetyl-10-((3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranosyl)oxy)-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-5,12-naphthacenedione hydrochloride Molecular Structur

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CAS No.23541-50-6 Daunorubicin hydrochlorideCompetitive Product

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CAS No.23541-50-6 Daunorubicin hydrochloride

  Package:1Mg;5Mg;10Mg...Storage:store in RT  Transportation:by air/sea  Application:Daunorubicin...

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CAS No.23541-50-6 Daunorubicin hydrochloride

5,12-Naphthacenedione,8-acetyl-10-[(3-amino-2,3,6-trideoxy-a-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-,hydrochloride (1:1), (8S,10S)-

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Daunorubicin HCl

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Daunorubicin HCl

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CAS No.23541-50-6 Daunorubicin hydrochloride

Assay:>99%Storage:-20℃ 2 years

M.Wt: 563.98 Formula: C27H29NO10.HCl Solubility: Unknown

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Daunorubicin Hydrochloride

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CAS No.23541-50-6 Daunorubicin hydrochloride

Cerubidine (Daunorubicin) is the hydrochloride salt of an anthracycline cytotoxic antibiotic produced by a strain of Streptomyces coeruleorubidus (IC50=0.5μM).

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CAS No.23541-50-6 Daunorubicin hydrochloride

CAS NO.: 23541-50-6 alias:Daunorubicin hydrochloride; rubidomycin hydrochloride; Daunorubicin, HCl Molecular formular:C27H29NO10.HCl Molecular weight: 563.98 Standard: Enterprise Standard Assay: ≥99.0% Packing: 1kg/tin contact details: Xingcheng Chempharm Co.,Ltd. T

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Reference

Tumoral drugs as possible blastogenic agents
Tumoral drugs as possible blastogenic agents. The problem of anti-blastic medication. Llombart, Antonio (Dep. Exp. Cancerol., Fac. Med.Some commonly used reagents like 51-21-8 and 52-24-4 are used in this experiment., Valencia, Spain). Oesterr. Z. Onkol., 3(3), 72-6 (English) 1976. CODEN: OZOKAN. DOCUMENT TYPE: Journal CA Section: 1 (Pharmacodynamics) Carcinogenic activity of drugs was studied by injecting into pregnant rats at the 20-21st day of gestation with doses twice that used in human therapeutics, and the drugs and the percentage of tumor formation were Oncotiotepa [52-24-4] 0, daunoblastine [23541-50-6] 3.3, vinblastine (I) [865-21-4] 9, bleomycine [11056-06-7] 12.8, 5-fluorouracil [51-21-8] 12.87, Lyovac [51109-87-6] 16.6, Genoxal [50-18-0] 17.14, and Natulan [366-70-1] 37.42%. The benign form of tumor predominated in all the tumors produced. The tumors were formed in the kidney, liver, mammary gland, nervous system, and skin. .
Xylose and galactose absorption in the rat jejunum in relation to the bacterial flora and after cytostatics
Xylose and galactose absorption in the rat jejunum in relation to the bacterial flora and after cytostatics. Boehmer, R.; Binder, R.; Rommel, K.; Dietrich, M.; Wolf, G. (Zent. Interdisziplinaere Med. Einheiten, Univ. Ulm, Ulm, Ger.). Z. Gastroenterol., 14(1), 30-40 (German) 1976. CODEN: ZGASAX. DOCUMENT TYPE: Journal CA Section: 1 (Pharmacodynamics) Conventional, germ-free, and decontaminated (antibiotic-treated) rats showed no differences in xylose [58-86-6] absorption by the perfused intestine in vivo, whereas galactose [59-23-4] absorption was decreased in germ-free and decontaminated rats compared to conventional rats. Three days after a single combined application of cytostatics (rubidomycin-HCl (I-HCl) [23541-50-6] 6 mg/kg, vincristine sulfate [2068-78-2] 0.5 mg/kg, prednisone [53-03-2] 2 mg/kg i.v.), xylose absorption was decreased in conventional and decontaminated rats compared to untreated animals, but was unaffected in germ-free rats. Galactose absorption was unaffected in conventional and decontaminated rats after cytostatic treatment, and was enhanced in germ-free animals. No morphol. changes were obsd. in the small intestinal mucosa of antibiotic- and cytostatic-treated rats .gtoreq. 3 days after treatment, compared to untreated animals. The drugs may affect sugar transport directly or indirectly through alterations in the intestinal flora.
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