CAS No.24169-02-6,Econazole nitrate Suppliers,MSDS download

Products Categories

Pharmaceutical (118)
Others (26)
Organic Chemicals (13)
Reagent (8)
Materials (2)
Agrochemicals (1)
Synthetic Flavours & Fragrances (1)
(1)

Basic Information

Molecular Structure:
CAS No.:	24169-02-6
Name:	Econazole nitrate
Article Data:	1

Formula:	C₁₈H₁₆Cl₃N₃O₄
Molecular Weight:	444.702
Synonyms:	(+-)-Econazole nitrate;1-(2,4-Dichloro-beta-((p-chlorobenzyl)oxy)phenethyl)imidazole nitrate;1-(2-((4-Chlorophenyl)methoxy)-2-(2,4-dichlorophenyl)ethyl)-1H-imidazole nitrate;
EINECS:	246-053-5
Density:	==
Melting Point:	162 °C
Solubility:	<0.1 g/100 mL at 19 ºC
Appearance:	White crystalline powder.
Hazard Symbols:	Xn,Xi
Risk Codes:	22-36/38-36/37/38
Safety:	26-36-36/37
PSA:	93.10000
LogP:	5.97690

Total:134 Page 1 of 4 1 2 3 4 Next>>

Post a RFQ

Cas No.:

Product Name:

Quantity:

Email:

Company name:

Valid Period:

Detailed Requirements:

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

What can I do for you?
Get Best Price

Get Best Price for 24169-02-6

Chemistry

IUPAC Name: 1-[2-[(4-Chlorophenyl)methoxy]-2-(2,4-dichlorophenyl)ethyl]imidazole; nitric acid
Canonical SMILES: C1=CC(=CC=C1COC(CN2C=CN=C2)C3=C(C=C(C=C3)Cl)Cl)Cl.[N+](=O)(O)[O-]
InChI: InChI=1S/C18H15Cl3N2O.HNO3/c19-14-3-1-13(2-4-14)11-24-18(10-23-8-7-22-12-23)16-6-5-15(20)9-17(16)21;2-1(3)4/h1-9,12,18H,10-11H2;(H,2,3,4)
InChIKey: DDXORDQKGIZAME-UHFFFAOYSA-N
Molecular Weight: 444.69634 [g/mol]
Molecular Formula: C₁₈H₁₆Cl₃N₃O₄
H-Bond Donor: 1
H-Bond Acceptor: 5
EINECS: 246-053-5
Appearance: White crystalline powder.
Melting Point: 162 °C
Classification Code of Econazole nitrate (CAS NO.24169-02-6): Antifungal; Mutation data; Reproductive Effect; Skin / Eye Irritant
Water Solubility: <0.1 g/100 mL at 19 °C
Product Categories: Aromatic Nitriles; Organics; ACTIVE PHARMACEUTICAL INGREDIENTS

Toxicity Data With Reference

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
dog	LD50	oral	> 160mg/kg (160mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD	Arzneimittel-Forschung. Drug Research. Vol. 25, Pg. 224, 1975.
guinea pig	LD50	oral	272mg/kg (272mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD	Arzneimittel-Forschung. Drug Research. Vol. 25, Pg. 224, 1975.
mouse	LD50	intraperitoneal	180mg/kg (180mg/kg)	BEHAVIORAL: TREMOR LUNGS, THORAX, OR RESPIRATION: CHRONIC PULMONARY EDEMA LUNGS, THORAX, OR RESPIRATION: DYSPNEA	Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 9, Pg. 643, 1978.
mouse	LD50	intravenous	38mg/kg (38mg/kg)	BEHAVIORAL: TREMOR LUNGS, THORAX, OR RESPIRATION: CHRONIC PULMONARY EDEMA LUNGS, THORAX, OR RESPIRATION: DYSPNEA	Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 9, Pg. 643, 1978.
mouse	LD50	oral	463mg/kg (463mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD	Arzneimittel-Forschung. Drug Research. Vol. 25, Pg. 224, 1975.
mouse	LD50	subcutaneous	750mg/kg (750mg/kg)	BEHAVIORAL: TREMOR LUNGS, THORAX, OR RESPIRATION: DYSPNEA LUNGS, THORAX, OR RESPIRATION: CHRONIC PULMONARY EDEMA	Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 9, Pg. 643, 1978.
rabbit	LD50	intravenous	85mg/kg (85mg/kg)	BEHAVIORAL: TREMOR LUNGS, THORAX, OR RESPIRATION: CHRONIC PULMONARY EDEMA LUNGS, THORAX, OR RESPIRATION: DYSPNEA	Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 9, Pg. 643, 1978.
rabbit	LD50	oral	431mg/kg (431mg/kg)		Gekkan Yakuji. Pharmaceuticals Monthly. Vol. 23, Pg. 1253, 1981.
rabbit	LD50	subcutaneous	650mg/kg (650mg/kg)	BEHAVIORAL: TREMOR LUNGS, THORAX, OR RESPIRATION: DYSPNEA LUNGS, THORAX, OR RESPIRATION: CHRONIC PULMONARY EDEMA	Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 9, Pg. 643, 1978.
rat	LD50	intraperitoneal	240mg/kg (240mg/kg)	BEHAVIORAL: TREMOR LUNGS, THORAX, OR RESPIRATION: CHRONIC PULMONARY EDEMA LUNGS, THORAX, OR RESPIRATION: DYSPNEA	Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 9, Pg. 643, 1978.
rat	LD50	intravenous	50mg/kg (50mg/kg)	BEHAVIORAL: TREMOR LUNGS, THORAX, OR RESPIRATION: CHRONIC PULMONARY EDEMA LUNGS, THORAX, OR RESPIRATION: DYSPNEA	Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 9, Pg. 643, 1978.
rat	LD50	oral	668mg/kg (668mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD	Arzneimittel-Forschung. Drug Research. Vol. 25, Pg. 224, 1975.
rat	LD50	subcutaneous	1360mg/kg (1360mg/kg)	BEHAVIORAL: TREMOR LUNGS, THORAX, OR RESPIRATION: CHRONIC PULMONARY EDEMA LUNGS, THORAX, OR RESPIRATION: DYSPNEA	Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 9, Pg. 643, 1978.

Safety Profile

The Hazard Codes of Econazole nitrate (CAS NO.24169-02-6): Xn, Irritant Xi
Risk Statements:
22: Harmful if swallowed
36/37/38: Irritating to eyes, respiratory system and skin
36/38: Irritating to eyes and skin
Safety Statements:
26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
36: Wear suitable protective clothing
36/37: Wear suitable protective clothing and gloves
WGK Germany: 3
RTECS: NI4450000

Specification

Econazole nitrate (CAS NO.24169-02-6), its Synonyms are (+-)-Econazole nitrate ; 1-(2,4-Dichloro-beta-((p-chlorobenzyl)oxy)phenethyl)imidazole nitrate ; 1-(2-((4-Chlorophenyl)methoxy)-2-(2,4-dichlorophenyl)ethyl)-1H-imidazole nitrate ; Econazole mononitrate ; Epi-pevaryl ; Gyno-Pevaryl 150 ; Gyno-pevaryl ; Ifenec ; Imidazole, 1-(2,4-dichloro-beta-((p-chlorobenzyl)oxy)phenethyl)-, mononitrate ; 1H-Imidazole, 1-(2-((4-chlorophenyl)methoxy)-2-(2,4-dichlorophenyl)ethyl)-, mononitrate ; 1H-Imidazole, 1-(2-((4-chlorophenyl)methoxy)-2-(2,4-dichlorophenyl)ethyl)-, mononitrate (9CI) ; 1H-Imidazole, 1-(2-((4-chlorophenyl)methoxy)-2-(2,4-dichlorophenyl)ethyl)-, nitrate ; Imidazole, 1-(2,4-dichloro-beta-((p-chlorobenzyl)oxy)phenethyl)-, mononitrate (8CI) .