Detail of "243669-48-9"

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Synthesis of novel 3-[(substituted aryl/heteroaryl)methylene]amino-2-methyl-5-thienylthieno[2,3-d]pyrimidi n-4(3H)-ones as possible antimicrobial agents

Synthesis of novel 3-[(substituted aryl/heteroaryl)methylene]amino-2-methyl-5-thienylthieno[2,3-d]pyrimidi n-4(3H)-ones as possible antimicrobial agents. Chambhare, R. V.; Bobade, A. S.; Khadse, B. G. (Department of Chemotherapy, Haffkine Institute for Training, Research and Testing, Mumbai 400 012, India). Indian Journal of Heterocyclic Chemistry, 12(1), 67-68 (English) 2002 Prof. R. S. Varma. CODEN: IJCHEI. ISSN: 0971-1627. DOCUMENT TYPE: Journal CA Section: 28 (Heterocyclic Compounds (More Than One Hetero Atom)) Section cross-reference(s): 1, 10 2-Methyl-3-amino-5-thienylthieno[2,3-d]pyrimidin-4(3H)-ones prepd.In this article, certain chemicals are used. One of their cas registry numbers is 243669-48-9 by reacting 2-acetamido-3-carbethoxy-5-thienylthiophene with hydrazine hydrate, were converted to the title compds. on condensation with arom. aldehydes using HOAc. The newly synthesized compds. were screened for their antibacterial, antifungal and antitubercular activities. All the compds. are inactive at a concn. of 200 ml/mL against Candida albicans, Trichophyton rubrum and T. mentagrophytes. All compds. were active as bactericides and antitubercular agents. E.g., 3-(2-fluoro-4-trifluoromethylbenzylidenamino)-2-methyl-5-(2-thienyl)thien o[2,3-d]pyrimidin-4(3H)-one exhibited a MIC of 0.1 mg/mL against Staphylococcus typhi and 2 mg/mL against Mycobacterium tuberculosis. .Some commonly used reagents like 243669-48-9 is used in this experiment..

Synthesis of novel 3-[(substituted aryl/heteroaryl)methylene]amino-2-methyl-5-thienylthieno[2,3-d]pyrimidi n-4(3H)-ones as possible antimicrobial agents

Synthesis of novel 3-[(substituted aryl/heteroaryl)methylene]amino-2-methyl-5-thienylthieno[2,3-d]pyrimidi n-4(3H)-ones as possible antimicrobial agents. Chambhare, R. V.; Bobade, A. S.; Khadse, B. G. (Department of Chemotherapy, Haffkine Institute for Training, Research and Testing, Mumbai 400 012, India). Indian Journal of Heterocyclic Chemistry, 12(1), 67-68 (English) 2002 Prof. R. S. Varma. CODEN: IJCHEI. ISSN: 0971-1627. DOCUMENT TYPE: Journal CA Section: 28 (Heterocyclic Compounds (More Than One Hetero Atom)) Section cross-reference(s): 1, 10 2-Methyl-3-amino-5-thienylthieno[2,3-d]pyrimidin-4(3H)-ones prepd.In this article, certain chemicals are used. One of their cas registry numbers is 243669-48-9 by reacting 2-acetamido-3-carbethoxy-5-thienylthiophene with hydrazine hydrate, were converted to the title compds. on condensation with arom. aldehydes using HOAc. The newly synthesized compds. were screened for their antibacterial, antifungal and antitubercular activities. All the compds. are inactive at a concn. of 200 ml/mL against Candida albicans, Trichophyton rubrum and T. mentagrophytes. All compds. were active as bactericides and antitubercular agents. E.g., 3-(2-fluoro-4-trifluoromethylbenzylidenamino)-2-methyl-5-(2-thienyl)thien o[2,3-d]pyrimidin-4(3H)-one exhibited a MIC of 0.1 mg/mL against Staphylococcus typhi and 2 mg/mL against Mycobacterium tuberculosis. .Some commonly used reagents like 243669-48-9 is used in this experiment..