CAS No.24916-51-6,Leucomycin V,9-O-[(2R,5S,6R)-5-(dimethylamino)tetrahydro-6-methyl-2H-pyran-2-yl]-, 3-acetate Suppliers

Detail of "24916-51-6"

CAS Number:

24916-51-6

Name:

Leucomycin V,9-O-[(2R,5S,6R)-5-(dimethylamino)tetrahydro-6-methyl-2H-pyran-2-yl]-, 3-acetate

Superlist Name:

Acetylspiramycin

Molecular Structure:

Formula:

C₄₅H₇₆N₂O₁₅

Molecular Weight:

885.09

Deleted CAS:

1403-58-3,1405-26-1,18810-02-1,23684-34-6,23684-35-7

Synonyms:

LeucomycinV, 9-O-[5-(dimethylamino)tetrahydro-6-methyl-2H-pyran-2-yl]-, 3-acetate,[9(2R,5S,6R)]-;Spiramycin B (7CI,8CI);Spiramycin II (6CI);Foromacidin B;Foromacidine B;Spiramycin 2;

Density:

1.21 g/cm³

Melting Point:

130-133 °C

Boiling Point:

916.7 °C at 760 mmHg

Flash Point:

508.2 °C

Solubility:

Soluble in most organic solvents

Appearance:

Crystalline solid

Reference

Effect of 24 antimicrobial drugs on polymorphonuclear leukocyte adherence: Effect of 24 antimicrobial drugs on polymorphonuclear leukocyte adherence. Li, Si Ying; Seow, W. K.; Thong, Y. H. (Kolling Inst. Med. Res., R. North Shore Hosp., Sydney 4101, Australia). Int. Arch. Allergy Appl. Immunol., 76(2), 151-5 (English) 1985. CODEN: IAAAAM. ISSN: 0020-5915. DOCUMENT TYPE: Journal CA Section: 1 (Pharmacology) The adherence of human neutrophils to nylon fiber microcolumns was markedly resistant to antimicrobial agents; no effect was obsd. with penicillin G [61-33-6], nafcillin [147-52-4], cephalothin [153-61-7], vancomycin [1404-90-6], bacitracin [1405-87-4], tetracycline [60-54-8], minocycline [10118-90-8], doxycycline [564-25-0], chloramphenicol [56-75-7], erythromycin [114-07-8], lincomycin [154-21-2], neomycin [1404-04-2], streptomycin [57-92-1], acetylspiramycin [24916-51-6], 5-fluorocytosine [2022-85-7], sulfisoxazole [127-69-5], tinidazole [19387-91-8], and primaquine [90-34-6]. Only 2 compds. enhanced adherence (oxytetracycline [79-57-2] and rifampicin [13292-46-1]) and only 4 suppressed adherence (colistin [1066-17-7], polymyxin B [1404-26-8], quinine [130-95-0], and chloroquine [54-05-7]) and then only at high concns.

Mutagenicity testing of eight antibiotics with the Ames method: Mutagenicity testing of eight antibiotics with the Ames method. Guo, Qiaosheng; Yuan, Zhihong (Jiangsu Munic. Inst. Drug Control, Peop. Rep. China). Kangshengsu, 10(1), 56-9 (Chinese) 1985. CODEN: KANGDS. ISSN: 0254-6116. DOCUMENT TYPE: Journal CA Section: 1 (Pharmacology) Eight antibiotics isobutylpiperazinylrifamycin [57184-22-2], medecamycin [35457-80-8], oxytetracycline [79-57-2], gentamicin [1403-66-3], kanamycin [59-01-8], erythromycin [114-07-8], lincomycin [154-21-2], and acetylspiramycin [24916-51-6] were tested for mutagenicity with the Ames method. The test strains were histidine-requiring Salmonella typhimurium mutants TA1535, TA1537, TA1538, TA98, and TA100. Only isobutylpiperazinylrifamycin (20 mg) was mutagenic by this method.

Detail of "24916-51-6"

Leucomycin V,9-O-[(2R,5S,6R)-5-(dimethylamino)tetrahydro-6-methyl-2H-pyran-2-yl]-, 3-acetate

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CAS No.24916-51-6 Acetylspiramycin

CAS No.24916-51-6 Acetylspiramycin

CAS No.24916-51-6 Acetylspiramycin

CAS No.24916-51-6 Acetylspiramycin

CAS No.24916-51-6 Acetylspiramycin

CAS No.24916-51-6 Acetylspiramycin

CAS No.24916-51-6 Acetylspiramycin

CAS No.24916-51-6 Acetylspiramycin

CAS No.24916-51-6 Acetylspiramycin

CAS No.24916-51-6 Acetylspiramycin

CAS No.24916-51-6 Acetylspiramycin

CAS No.24916-51-6 Acetylspiramycin

CAS No.24916-51-6 Acetylspiramycin

CAS No.24916-51-6 Acetylspiramycin

CAS No.24916-51-6 Acetylspiramycin

CAS No.24916-51-6 Acetylspiramycin

CAS No.24916-51-6 Acetylspiramycin

Reference