Detail of "25501-32-0"

Reference

Modeling of the separation of two enantiomers using a microbore column

Modeling of the separation of two enantiomers using a microbore column. Zhou, Dongmei; Kaczmarski, Krzysztof; Cavazzini, Alberto; Liu, Xiaoda; Guiochon, Georges (Department of Chemistry, The University of Tennessee, Knoxville, TN 37996-1600, USA). Journal of Chromatography, A, 1020(2), 199-217 (English) 2003 Elsevier Science B.V. CODEN: JCRAEY. ISSN: 0021-9673. DOCUMENT TYPE: Journal CA Section: 80 (Organic Analytical Chemistry) Section cross-reference(s): 66 A microbore column packed with Chiralcel OB (cellulose tribenzoate coated silica) was used for the measurement of the single and competitive equil.-isotherm data of the 1-indanol enantiomers by frontal anal. The amt. of sample needed for the isotherm data acquisition was ~20 times less than that required with a conventional column. The data obtained were fitted to different single and competitive isotherm models. Both the single and the competitive data sets fitted best to the same Bilangmuir (BL) isotherm model with small differences in the numerical values of the parameters. The best fitted Bilangmuir single and competitive isotherm models were used to predict the overloaded exptl. profiles of both pure enantiomers, of the racemic mixt., and of different enantiomeric mixts. All the calcd. profiles were in excellent agreement with the exptl. ones. This agreement confirms that in many chiral sepns., the competitive isotherms can be derived from data acquired from the mere racemic mixt. 697-64-3 and 25501-32-0 which are cas registry numbers of substances are two of reagents here. with a sufficient accuracy for a correct prediction of the band profiles of all kinds of enantiomer mixts., making possible the computer-assisted optimization of the exptl. conditions. .

Heterogeneous Adsorption of 1-Indanol on Cellulose Tribenzoate and Adsorption Energy Distribution of the Two Enantiomers

Some chemicals with cas registry numbers like 697-64-3 and 25501-32-0 are also used. Heterogeneous Adsorption of 1-Indanol on Cellulose Tribenzoate and Adsorption Energy Distribution of the Two Enantiomers. Goetmar, Gustaf; Zhou, Dongmei; Stanley, Brett J.; Guiochon, Georges (Department of Chemistry, The University of Tennessee, Knoxville, TN 37996-1600, USA). Analytical Chemistry, 76(1), 197-202 (English) 2004 American Chemical Society. CODEN: ANCHAM. ISSN: 0003-2700. DOCUMENT TYPE: Journal CA Section: 66 (Surface Chemistry and Colloids) The distributions of the adsorption energies (AED) of two enantiomers, (R)-1- indanol and (S)-1-indanol, on a chiral stationary phase were measured and the results are discussed. The chiral phase used is made of cellulose tribenzoate coated on porous silica. The AEDs were detd. using the expectation maximization method, a numerical method that uses directly the raw exptl. isotherm data, inverts this set of data into an AED, and introduces no arbitrary information in the calcn. However, it uses the Langmuir equation as the local isotherm. The exptl. data fit very well to the bi-Langmuir isotherm model for the more retained enantiomer. Our results show that the AEDs of these two enantiomers have no energy modes that would be identical (same mean energy, mode profile, and mode area), in contrast to numerous cases previously studied, e.g., that of the b-blockers on a Cel7A column. This indicates a significantly different retention mechanism. .