Detail of "2577-62-0"

CAS Number:
2577-62-0
Name:
Heptanedioic acid,2,6-diamino-, (2R,6R)-rel-
Molecular Structure:
Formula:
C7H14 N2 O4
Molecular Weight:
190.2
Synonyms:
Heptanedioicacid, 2,6-diamino-, (R*,R*)-(?à)- (8CI); (?à)-Diaminopimelicacid; (?à)-a,e-Diaminopimelic acid; DL-2,6-Diaminopimelic acid; DL-a,e-Diaminopimelic acid
Density:
1.344g/cm³
Melting Point:
~295 °C (dec.)(lit.)
Boiling Point:
426.7°Cat760mmHg
Flash Point:
211.8°C
Hazard Symbols:
Risk Codes:
36/37/38
Safety:
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-36/37
WGK Germany 3

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Effects of lysine analogs on Penicillium chrysogenum: Effects of lysine analogs on Penicillium chrysogenum. Friedrich, C. G.; Demain, A. L. (Dep. Nutr. Food Sci., Massachusetts Inst. Technol., Cambridge, Mass., USA). Appl. Environ. Microbiol., 34(6), 706-9 (English) 1977. CODEN: AEMIDF. DOCUMENT TYPE: Journal CA Section: 3 (Biochemical Interactions) Section cross-reference(s): 16 Compds. structurally related to lysine were tested against P. chrysogenum Wis. 54-1255 for inhibition of growth, sporulation, and benzylpenicillin [61-33-6] formation. This strain was relatively resistant to lysine analogs. The compds. that were the more active inhibitors of growth and whose activities were reversed by L-lysine-HCl [657-27-2] were 2,6-diamino-4-hexynoic acid-2HCl [65579-76-2], N-e-methyllysine-HCl [7622-29-9], N-a-methyllysine [7431-89-2], and DL-a,e-diaminopimelic acid [2577-62-0]. These 4 compds. also inhibited sporulation, which was more sensitive to inhibition than growth was. Analogs strongly inhibiting benzylpenicillin formation by resting mycelia were diaminohexynoic acid and N-e-methyllysine. The action of the most active analog (diaminohexynoic acid) on penicillin synthesis was reversed by DL-a-aminoadipic acid [626-71-1].