CAS No.26171-23-3,1H-Pyrrole-2-aceticacid, 1-methyl-5-(4-methylbenzoyl)- Suppliers

Detail of "26171-23-3"

CAS Number:

26171-23-3

Name:

1H-Pyrrole-2-aceticacid, 1-methyl-5-(4-methylbenzoyl)-

Superlist Name:

Tolmetin

Molecular Structure:

Formula:

C₁₅H₁₅NO₃

Molecular Weight:

257.29

Synonyms:

Pyrrole-2-aceticacid, 1-methyl-5-p-toluoyl- (8CI);1-Methyl-5-p-toluoylpyrrole-2-acetic acid;5-[(p-Tolyl)carbonyl]-1-methylpyrrole-2-acetic acid;McN 2559;Tolmetine;

EINECS:

247-497-2

Density:

1.18 g/cm³

Melting Point:

156 °C

Boiling Point:

483.19 °C at 760 mmHg

Flash Point:

246.025 °C

Solubility:

222 mg/L in water

Reference

High-pressure liquid chromatographic (HPLC) determination of tolmetin and its major metabolite in plasma: High-pressure liquid chromatographic (HPLC) determination of tolmetin and its major metabolite in plasma. Ayres, J. W.; Sakmar, E.; Hallmark, M. R.; Wagner, J. G. (Coll. Pharm., Univ. Michigan, Ann Arbor, Mich., USA). Res. Commun. Chem. Pathol. Pharmacol., 16(3), 475-83 (English) 1977. CODEN: RCOCB8. DOCUMENT TYPE: Journal CA Section: 1 (Pharmacodynamics) A high-pressure liq. chromatog. assay was developed for the quant. detn. of tolmetin (I) [26171-23-3] and its major metabolite in plasma. Detn. of I was compared to a previously reported spectrophotometric assay method. The std. curves were evaluated statistically and daily std. curves were preferred over a pooled std. curve. The method was applied to samples of one subject's plasma contg. both I and its major metabolite.

Effect of tolmetin on DNA metabolism: Effect of tolmetin on DNA metabolism. Klein, G.; Wottawa, A.; Altmann, H. (Med. Universitaetsklin. Graz, Vienna, Austria). Therapiewoche, 27(12), 2198, 2200, 2203 (German) 1977. CODEN: THEWA6. DOCUMENT TYPE: Journal CA Section: 1 (Pharmacodynamics) Tolmetin (I) [26171-23-3] (100-150 .mu.g/mL) dose-dependently inhibited DNA synthesis by mouse spleen cells and human lymphocytes in vitro. I did not effect DNA repair after irradn. of the cells.

Detail of "26171-23-3"

1H-Pyrrole-2-aceticacid, 1-methyl-5-(4-methylbenzoyl)-

Famous Chemical Enterprises

Related products

Other Products

Supplier Location

Business Type

Certificates

CAS No.26171-23-3 Tolmetin

CAS No.26171-23-3 Tolmetin

CAS No.26171-23-3 Tolmetin

CAS No.26171-23-3 Tolmetin

CAS No.26171-23-3 Tolmetin

CAS No.26171-23-3 Tolmetin

CAS No.26171-23-3 Tolmetin

CAS No.26171-23-3 Tolmetin

CAS No.26171-23-3 Tolmetin

CAS No.26171-23-3 Tolmetin

CAS No.26171-23-3 Tolmetin

Reference