CAS No.26189-59-3,1-Propen-1-amine,1-chloro-N,N,2-trimethyl- Suppliers,MSDS download

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CAS Number:
26189-59-3
Name:
1-Propen-1-amine,1-chloro-N,N,2-trimethyl-
Superlist Name:
1-Chloro-N,N,2-trimethylpropenylamine
Formula:
C₆H₁₂ClN
Molecular Structure:
Synonyms:
Propenylamine,1-chloro-N,N,2-trimethyl- (8CI);1-Chloro-1-(dimethylamino)-2-methylpropene;1-Chloro-N,N,2-trimethyl-1-propenylamine;1-Chloro-N,N-dimethyl-2-methylprop-1-en-1-amine;N-(1-Chloro-2-methylprop-1-enyl)-N,N-dimethylamine;
Molecular Weight:
133.62
Density:
0.958 g/cm³
Boiling Point:
161.022 °C at 760 mmHg
Flash Point:
51.185 °C
Appearance:
Colorless to yellow liquid
Hazard Symbols:
C
Risk Codes:
10-34
Safety:
16-26-36/37/39-45Details
Transport Information:
UN 2734

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Prenyl substituted cyclobutanones as squalene synthetase inhibitors: Prenyl substituted cyclobutanones as squalene synthetase inhibitors. Ortiz de Montellano, Paul R.; Castillo, Rafael (Sch. Pharm., Univ. California, San Francisco, Calif., USA). Tetrahedron Lett., (46), 4115-18 (English) 1976. CODEN: TELEAY. DOCUMENT TYPE: Journal CA Section: 24 (Alicyclic Compounds) Section cross-reference(s): 7 The cyclobutanones I (R = H, tetrahydrogeranyl) (II and III, resp.) were prepd. by the reaction between 4,8,12-trimethyl-1,3,7,11-tridecatetraene and the amines IV in CH2Cl2 contg. AgBF4 at -78.degree.. I (R = geranyl) could not be prepd. by a similar reaction, probably because of intramol. cyclizations of the keteneimmonium cationic intermediate formed from the dimethylchloroamine. A 10-15% inhibition of yeast squalene synthetase was obsd. 26189-59-3 and 62235-09-0 are just another two chemicals used in this study. with II and III at 5 mM concn. .

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