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2623-23-6

Basic Information
CAS No.: 2623-23-6
Name: (1R)-(-)-Menthyl acetate
Article Data: 194
Molecular Structure:
Molecular Structure of 2623-23-6 ((1R)-(-)-Menthyl acetate)
Formula: C12H22O2
Molecular Weight: 198.305
Synonyms: Cyclohexanol,5-methyl-2-(1-methylethyl)-, acetate, (1R,2S,5R)- (9CI);Cyclohexanol,5-methyl-2-(1-methylethyl)-, acetate, [1R-(1a,2b,5a)]-;Menthol, acetate,(1R,3R,4S)-(-)- (8CI);(-)-Menthol acetate;(-)-Menthyl acetate;(-)-p-Menthylacetate;(1R,2S,5R)-5-Methyl-2-(1-methylethyl)cyclohexanol acetate;Acetic acid(R)-menthyl ester;L-Menthyl acetate;NSC 3722;NSC 52970;l-(-)-Menthylacetate;l-Menthol acetate;
EINECS: 220-076-0
Density: 0.92 g/cm3
Melting Point: <25 °C
Boiling Point: 229.1 °C at 760 mmHg
Flash Point: 92.2 °C
Solubility: 23.2mg/L at 20℃
Safety: 24/25
PSA: 26.30000
LogP: 3.01030
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  • (1R)-(-)-Menthyl acetate

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    (1R)-(-)-Menthyl acetate

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Chemistry

Product Name: (1R)-(-)-Menthyl acetate (2623-23-6)


Molecular Formula: C12H22O2
Molecular Weight: 198.3g/mol
Mol File: 2623-23-6.mol
Einecs: 220-076-0
Appearance: Colorless liquid
Melting Point:
Boiling point: 229-230 °C(lit.)
Flash Point: 92.2 °C
Density: 0.92 g/mL at 25 °C(lit.)
Refractive index: n20/D 1.447(lit.)
Product Categories: Pharmaceutical Raw Materials; Monocyclic Monoterpenes; Biochemistry; Terpenes; Esters; Chiral Building Blocks; EstersAlphabetic; M; MEA - MES; Organic Building Blocks
Synonyms of  (1R)-(-)-Menthyl acetate (2623-23-6): 2-isopropyl-5-methyl-,acetate,l-cyclohexan-1-o ; 5-methyl-2-(1-methylethyl)-,acetate,[1R-(1.alpha.,2.beta.,5.alpha.)]-Cyclohexanol ; acetate,(1r,3r,4s)-(-)-mentho ; aceticacid(1R)-menthylester ; cyclohexanol,5-methyl-2-(1-methylethyl)-,acetate,(1r-(1alpha,2beta,5alpha) ; cyclohexanol,5-methyl-2-(1-methylethyl)-,acetate,[1theta-(1alpha,2beta,5 ; l-p-menth-3-ylacetate;p-menth-3-ylester,l-aceticaci .

Uses

GB 2760 - 1996 provides for the use of edible spices. (1R)-(-)-Menthyl acetate (2623-23-6) is mainly used in the preparation of mint, fruit and berries fragrance.

Production

By pepper mint oil in the sample derived from a single (l type).
In the presence of anhydrous sodium acetate, acetic anhydride by the menthol and the reaction by washing, distillation derived (dl type).

 

Toxicity Data With Reference

Low toxicity by ingestion and skin contact. A skin irritant. When heated to decomposition it emits acrid smoke and irritating fumes.

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
rabbit LD50 skin > 5gm/kg (5000mg/kg)   Food and Cosmetics Toxicology. Vol. 14, Pg. 477, 1976.
rat LD50 oral > 5gm/kg (5000mg/kg)   Food and Cosmetics Toxicology. Vol. 14, Pg. 477, 1976.

Consensus Reports

Reported in EPA TSCA Inventory.

Safety Profile

Safety Information of (1R)-(-)-Menthyl acetate (2623-23-6):
Safety Statements: 24/25
24:  Avoid contact with skin 
25:  Avoid contact with eyes