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2636-26-2

Basic Information
CAS No.: 2636-26-2
Name: CYANOPHOS
Article Data: 9
Molecular Structure:
Molecular Structure of 2636-26-2 (CYANOPHOS)
Formula: C9H10 N O3 P S
Molecular Weight: 243.223
Synonyms: Phosphorothioicacid, O,O-dimethyl ester, O-ester with p-hydroxybenzonitrile (7CI,8CI);Phosphorothioic acid, O-p-cyanophenyl O,O-dimethyl ester (6CI); BAY 34727;CYAP; Ciafos; Cyanofos; Cyanophos; Cyanox; O,O-Dimethyl O-(4-cyanophenyl)phosphorothioate; O,O-Dimethyl O-(p-cyanophenyl) phosphorothioate; S 4084;Sumitomo S 4084
EINECS: 220-130-3
Density: 1.3 g/cm3
Melting Point: 14-15oC
Boiling Point: 322.3 °C at 760 mmHg
Flash Point: 148.7 °C
Solubility: 46 mg l-1 (30 °C)
Hazard Symbols: Poison. A cholinesterase inhibitor.
Risk Codes: 21/22 50/53
Safety: Poison by ingestion. Moderately toxic by skin contact and intraperitoneal routes. An insecticide and cholinesterase inhibitor. See also PARATHION. When heated to decomposition it emits toxic fumes of NOx, POx, CN, and SOx.
PSA: 93.38000
LogP: 3.10498
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Chemistry

Product Name: Cyanophos (CAS NO.2636-26-2)


Molecular Formula: C9H10NO3PS
Molecular Weight: 243.22g/mol
Mol File: 2636-26-2.mol
Einecs: 220-130-3
Appearance: Yellow to reddish-yellow transparent liquid
Boiling point: 322.3 °C at 760 mmHg
Storage Temperature: 0-6°C
Flash Point: 148.7 °C
Density: 1.3 g/cm3
Surface Tension: 54.7 dyne/cm
Enthalpy of Vaporization: 56.41 kJ/mol
Vapour Pressure: 0.000282 mmHg at 25°C
XLogP3: 2.7
H-Bond Donor: 0
H-Bond Acceptor: 4
Product Categories: Insecticide

Uses

 Cyanophos (CAS NO.2636-26-2) is used to control fruit, vegetables and ornamental plants of Lepidoptera pests, also can prevent and control cockroaches, flies and mosquitoes like health pests. It can also be used to control rice stem borer, yellow rice borer, leaf roller, rice bud worms, leafhoppers, thrips, pests such as Pieris rapae

Production

 Cyanophos (CAS NO.2636-26-2) can be O, O-dimethyl sulfur chloride by phosphate and cyano-phenol reaction. In the presence of anhydrous potassium carbonate, it can be O, O-2-methyl thiophosphoryl chloride with the reaction of hydroxyl nitrile. It also can be p-nitrile from 4 - hydroxybenzoic acid and urea, phosphorus pentasulfide reaction.

Toxicity Data With Reference

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
bird - wild LD50 oral 3mg/kg (3mg/kg)   Journal de Toxicologie Clinique et Experimentale. Vol. 6(3), Pg. 175, 1986.
chicken LD50 oral 23500ug/kg (23.5mg/kg) PERIPHERAL NERVE AND SENSATION: SPASTIC PARALYSIS WITH OR WITHOUT SENSORY CHANGE

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

BEHAVIORAL: ATAXIA
Toxicology and Applied Pharmacology. Vol. 11, Pg. 49, 1967.
mammal (species unspecified) LD50 skin 2010mg/kg (2010mg/kg)   Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 21(7), Pg. 34, 1977.
mouse LD50 intraperitoneal 350mg/kg (350mg/kg)   Agricultural and Biological Chemistry. Vol. 26, Pg. 257, 1962.
mouse LD50 oral 720mg/kg (720mg/kg)   Yakkyoku. Pharmacy. Vol. 37, Pg. 427, 1986.
mouse LD50 skin > 2gm/kg (2000mg/kg)   Agricultural and Biological Chemistry. Vol. 26, Pg. 257, 1962.
mouse LD50 subcutaneous 1080mg/kg (1080mg/kg)   Agricultural and Biological Chemistry. Vol. 26, Pg. 257, 1962.
mouse LD50 unreported 720mg/kg (720mg/kg)   Rinsho Shinkeigaku. Clinical Neurology. Vol. 23, Pg. 101, 1983.
rat LD50 oral 215mg/kg (215mg/kg)   Agricultural and Biological Chemistry. Vol. 26, Pg. 257, 1962.
rat LD50 skin 800mg/kg (800mg/kg)   "Pesticide Index," Frear, E.H., ed., State College, PA, College Science Pub., 1969Vol. 5, Pg. 62, 1976.
rat LD50 unreported 580mg/kg (580mg/kg)   Rinsho Shinkeigaku. Clinical Neurology. Vol. 23, Pg. 101, 1983.

Consensus Reports

Cyanide and its compounds are on the Community Right-To-Know List. On EPA Extremely Hazardous Substances List.

Safety Profile

Safety Information of Cyanophos (CAS NO.2636-26-2):
Hazard Codes: Xn,N
Risk Statements: 21/22-50/53
21:  Harmful in contact with skin 
22:  Harmful if swallowed 
50:  Very Toxic to aquatic organisms
53:  May cause long-term adverse effects in the aquatic environment
Safety Statements: 36/37-60-61
36:  Wear suitable protective clothing  
37:  Wear suitable gloves
60:  This material and/or its container must be disposed of as hazardous waste 
61:  Avoid release to the environment. Refer to special instructions safety data sheet 

Specification

 Cyanophos ,its CAS NO. is 2636-26-2,the synonyms is (O-p-cyanophenyl-o,o-dimethylphosphorothioate) ; 4-(Dimethoxyphosphinothioyloxy)benzonitrile ; Ai3-25675 ; Bay 34727 ; Bayer 34727 ; Caswellno268a .