Detail of "2652-77-9"

Reference

Pyrazoles from etacrynic acid

Pyrazoles from etacrynic acid. Goerlitzer, K.; Diers, K. (Institut Pharmazeutische Chemie, Technische Universitaet Braunschweig, Braunschweig D-38106, Germany). Pharmazie, 52(1), 32-34 (German) 1997 Govi-Verlag Pharmazeutischer Verlag. CODEN: PHARAT. ISSN: 0031-7144.Several substances with their cas registry numbers 2652-77-9 and 186604-59-1 may be metioned in this study. DOCUMENT TYPE: Journal CA Section: 28 (Heterocyclic Compounds (More Than One Hetero Atom)) Michael addn. of etacrynic acid with 1,2-diphenylpyrazolidine-3,5-dione or 5-methyl-2-phenyl-3-pyrazolone yields the compds. I (R = Ph, R1R2 = O, R3 = H; R = H, R1 = Me, R2R3 = bond). Pyrazolidinedione I (R = Ph, R1R2 = O, R3 = H) cyclizes by melting with NH4OAc to form the pyrazolo[3,4-b]pyridine II. The 4,5-dihydropyrazoles III (R = Ph, H, Ac) are obtained by reaction of etacrynic acid with appropriate hydrazines. .

1,2-Diphenyl-3,5-dioxo-4-(3'-chlorocrotyl)pyrazolidine

1,2-Diphenyl-3,5-dioxo-4-(3'-chlorocrotyl)pyrazolidine. Indruch, Miroslav; Gabriel, Jiri; Mayer, Jiri (Czech.In this study， 2652-77-9 and 926-57-8 are also used. ). Czech. CS 207171 B 1 Nov 1983,3 pp. (Czech). (Czechoslovakia). CODEN: CZXXA9. CLASS: IC: C07D231-36. APPLICATION: CS 80-19 2 Jan 1980. DOCUMENT TYPE: Patent CA Section: 28 (Heterocyclic Compounds (More Than One Hetero Atom)) Alkylation of 1,2-diphenyl-3,5-dioxopyrazolidine with ClCH2CH:CClMe in aq. NaOH at 30-32° gives purer title product (I) in the presence of a water-immiscible solvent, such as PhMe, PhCl, or CHCl:CCl2, which takes up contaminants present in the reaction suspension. Filtration of the solid phase gives 64-68% I. .