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Detail of > 27203-92-5

  • CAS Number:
  • 27203-92-5
  • Name:
  • Cyclohexanol,2-[(dimethylamino)methyl]-1-(3-methoxyphenyl)-, (1R,2R)-rel-

  • Superlist Name:
  • Tramadol
  • Formula:
  • C16H25NO2
  • Molecular Structure:
  • Synonyms:
  • Cyclohexanol,2-[(dimethylamino)methyl]-1-(m-methoxyphenyl)- (8CI);CG 315E;E 265;Racemic tramadol;Tiparol;Tramadis;Tramadol Contramid;Tramadon;Trapidol;U 26255A;Zytram;cis-Tramadol;
  • Molecular Weight:
  • 263.42
  • EINECS:
  • 248-319-6
  • Density:
  • 1.047 g/cm3
  • Melting Point:
  • 178-181 °C
  • Boiling Point:
  • 388.1 °C at 760 mmHg
  • Flash Point:
  • 188.5 °C
  • Appearance:
  • Light yellow oil
  • Hazard Symbols:
  • HarmfulXn
  • Risk Codes:
  • 22
  • Transport Information:
  • UN 2811 6.1/PG 3
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Reference

Algo-pupillometric study of the analgesic effect of tramadol
Algo-pupillometric study of the analgesic effect of tramadol. Krueger, H.; Mueller-Limmroth, W. (Inst. Arbeitsphysiol., Tech. Univ. Muenchen, Munich, Ger.). Arzneim.-Forsch., 28(1A), 176-8 (German) 1978. CODEN: ARZNAD. ISSN: 0004-4172. DOCUMENT TYPE: Journal CA Section: 1 (Pharmacodynamics) Tramadol (I) [27203-92-5] (75 and 150 mg) given orally to volunteers caused slight miosis 3 h postadministration. The course of the analgesic algopupillogram was biphasic reaching a max. at 30 min and a min. at 4 h after administration. At the time of max. effect, the pupillary reaction of subjects given 75 or 150 mg I was equal to that of untreated subjects to whom only 60 or 10%, resp., of the stimulus intensity was applied.
The effect of tramadol on the physical and psychomotor performance in man
The effect of tramadol on the physical and psychomotor performance in man. Mueller-Limmroth, W.; Krueger, H. (Inst. Arbeitsphysiol., Tech. Univ. Muenchen, Munich, Ger.). Arzneim.-Forsch., 28(1A), 179-80 (German) 1978. CODEN: ARZNAD. ISSN: 0004-4172. DOCUMENT TYPE: Journal CA Section: 1 (Pharmacodynamics) Tramadol (I) [27203-92-5] (75 mg) given to volunteers did not affect the phys. working capacity nor affect psychomotor performance in the eye-hand coordination test.

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