Reference

Potential histamine H2-receptor antagonists: ranitidine analogs containing 2-amino-5(6)-substituted benzimidazole moieties

Potential histamine H2-receptor antagonists: ranitidine analogs containing 2-amino-5(6)-substituted benzimidazole moieties. (1). Sorba, Giovanni; Garrone, Adele; Serafino, Anna; Gasco, Alberto; Orsetti, Marco (Inst. Pharm. Toxicol. Chem., Univ.Some commonly used reagents like 27231-36-3 and 106135-31-3 are used in this experiment. Turin, Turin 10125, Italy). Eur. J. Med. Chem.--Chim. Ther., 21(5), 391-5 (English) 1986. CODEN: EJMCA5. ISSN: 0223-5234. DOCUMENT TYPE: Journal CA Section: 1 (Pharmacology) Section cross-reference(s): 28 A series of ranitidine analogs (I: R = H, Me, OMe, Cl, CONH2, CN, and NO2) were synthesized and tested for its in vitro H2-antagonism by using the histamine induced guinea pig atria chronotropic response. These substances generally display good H2-antagonist activity. Some considerations of the structure relationships are also discussed, in particular the physicochem. properties of the benzimidazole moiety. .

Trans-1,2-bis(diphenylphosphino)ethene as bridging ligand in thione-S-ligated dimeric copper(I) chloride complexes

Trans-1,2-bis(diphenylphosphino)ethene as bridging ligand in thione-S-ligated dimeric copper(I) chloride complexes. Aslanidis, P.; Cox, P. J.; Divanidis, S.; Karagiannidis, P. (Inorganic Chemistry Laboratory, Faculty of Chemistry, Aristotle University of Thessaloniki, Thessaloniki GR- 541 24, Greece). Inorganica Chimica Acta, 357(14), 4231-4239 (English) 2004 Elsevier B.V. CODEN: ICHAA3. ISSN: 0020-1693. DOCUMENT TYPE: Journal CA Section: 78 (Inorganic Chemicals and Reactions) Section cross-reference(s): 75 Several mixed-ligand complexes were prepd. by treatment of Cu(I) chloride with equimolar amts. of trans-1,2-bis(diphenylphosphino)ethene (trans-dppen) in MeCN followed by the addn. of a methanolic soln. of one equiv. of a heterocyclic thione (L). The novel complex compds. were characterized by single-crystal x-ray diffraction, 1H NMR and IR spectroscopy as well as by elemental analyses and m.ps. The x-ray structures of three examples confirm that the compds.In this experiment, several chemicals are used like 27231-36-3 and 821771-69-1 are homobimetallic dimers [CuCl(m2-trans-dppen)(L)]2 contg. two tetrahedral coordination units joined by two trans-dppen bridges. .