Detail of "27532-96-3"

CAS Number:
27532-96-3
Name:
Glycine tert butyl ester hydrochloride
Molecular Structure:
Formula:
C₆H₁₃NO₂^.HCl
Molecular Weight:
167.63
Synonyms:
Glycine,1,1-dimethylethyl ester, hydrochloride (9CI);Glycine, tert-butyl ester,hydrochloride (7CI,8CI);1,1-Dimethylethyl glycinate hydrochloride;2-Aminoacetic acid tert-butyl ester hydrochloride;Glycine tert-butyl esterhydrochloride;Glycine tert-butyl ester monohydrochloride;tert-Butylglycinatehydrochloride;H-Gly-OtBu·HCl;Glycine,1,1-dimethylethyl ester, hydrochloride (1:1);
Density:
0.973 g/cm³
Melting Point:
141-143 °C(lit.)
Boiling Point:
145.7 °C at 760 mmHg
Flash Point:
20.7 °C
Solubility:
0.1 g/mL in water, clear, colorless
Appearance:
Crystalline
Risk Codes:
36/37/38
Safety:
24/25 Details

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Reference

Mycoloyl peptide and other lipopeptide adjuvants from higher aldoketene dimers: Mycoloyl peptide and other lipopeptide adjuvants from higher aldoketene dimers. Metzger, Joerg; Jung, Guenther (Inst. Org. Chem.Chemicals with cas numbers 15100-75-1 and 27532-96-3 also play role., Univ. Tuebingen, Tuebingen D-7400, Fed. Rep. Ger.). Angew. Chem., 99(4), 343-5 (German) 1987. CODEN: ANCEAD. ISSN: 0044-8249. DOCUMENT TYPE: Journal CA Section: 34 (Amino Acids, Peptides, and Proteins) Section cross-reference(s): 15 RCH2COCHRCO-X-OCMe3 (I; R = m-C16H33; X = Gly, Ala, Ser, Phe, etc.) were prepd. by treating aldoketene dimer II with H-X-OCMe3 in the presence of DMAP. I were reduced by NaBH4 to give the corresponding RCH2CH(OH)CHRCO-X-OCMe3. Mitogenic activities of related lipopeptides are given. .

Synthesis and in vitro antitumor activity of phthalimide polymers containing podophyllotoxin: All Rights Reserved. Synthesis and in vitro antitumor activity of phthalimide polymers containing podophyllotoxin. Lee, Neung-Ju; Jeong, In-Cheol; Cho, Moo-Youn; Jeon, Chang-Wan; Yun, Byung-Cheol; Kim, Young-Ok; Kim, Seon-Hee; Chung, Ildoo ( Department of Premedical Sciences, College of Medicine, Kosin University, Pusan 602-703, S. Korea). European Polymer Journal, 42(12), 3352-3359 (English) 2006 Elsevier Ltd. CODEN: EUPJAG. ISSN: 0014-3057. DOCUMENT TYPE: Journal CA Section: 1 (Pharmacology) Section cross-reference(s): 35 Polymer-linked PT (podophyllotoxin) conjugates have been designed to improve the therapeutic efficacy of PT. A new PT-conjugate, 3,6-endo-methylene-1,2,3,6-tetrahydrophthalimido-acetamidoglycinylgl ycine podophyllotoxin ester (ETPA-gly-gly-PT), was synthesized by covalently coupling its hydroxyl group onto the phthalimido monomer through a glycine-glycine-glycine spacer. Its homo- and copolymer with acrylic acid (AA) were prepd. by photopolymn. using 2,2-dimethoxy-2-phenylacetophenone (DMP) as a photoinitiator. ETPA-gly-gly-PT and its polymers were characterized by IR and proton NMR spectra. The ETPA-gly-gly-PT content in the copolymer obtained by elemental anal.Several substances with their cas registry numbers 918492-88-3 and 27532-96-3 may be metioned in this study. was 44%. The no.-av. mol. wts. of the polymers detd. by gel permeation chromatog. were as follows: Mn = 13,500 for poly(ETPA-gly-gly-PT), Mn = 17,000 for poly(ETPA-gly-gly-PT-co-AA). The in vitro antitumor activity of these conjugates and polymers were detd. and used to evaluate the potential applications in antitumor drugs. The IC50 values indicated that the synthesized ETPA-gly-gly-PT and its polymers against cancer cells were much better inhibitors than PT. .

Detail of "27532-96-3"

Glycine tert butyl ester hydrochloride

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CAS No.27532-96-3 Glycine tert butyl ester hydrochloride

CAS No.27532-96-3 Glycine tert butyl ester hydrochloride

CAS No.27532-96-3 Glycine tert butyl ester hydrochloride

CAS No.27532-96-3 Glycine tert butyl ester hydrochloride

CAS No.27532-96-3 Glycine tert butyl ester hydrochloride

CAS No.27532-96-3 Glycine tert butyl ester hydrochloride

CAS No.27532-96-3 Glycine tert butyl ester hydrochloride

CAS No.27532-96-3 Glycine tert butyl ester hydrochloride

CAS No.27532-96-3 Glycine tert butyl ester hydrochloride

CAS No.27532-96-3 Glycine tert butyl ester hydrochloride

CAS No.27532-96-3 Glycine tert butyl ester hydrochloride

CAS No.27532-96-3 Glycine tert butyl ester hydrochloride

CAS No.27532-96-3 Glycine tert butyl ester hydrochloride

CAS No.27532-96-3 Glycine tert butyl ester hydrochloride

CAS No.27532-96-3 Glycine tert butyl ester hydrochloride

CAS No.27532-96-3 Glycine tert butyl ester hydrochloride

CAS No.27532-96-3 Glycine tert butyl ester hydrochloride

CAS No.27532-96-3 Glycine tert butyl ester hydrochloride

CAS No.27532-96-3 Glycine tert butyl ester hydrochloride

CAS No.27532-96-3 Glycine tert butyl ester hydrochloride

CAS No.27532-96-3 Glycine tert butyl ester hydrochloride

CAS No.27532-96-3 Glycine tert butyl ester hydrochloride

CAS No.27532-96-3 Glycine tert butyl ester hydrochloride

CAS No.27532-96-3 Glycine tert butyl ester hydrochloride

CAS No.27532-96-3 Glycine tert butyl ester hydrochloride

CAS No.27532-96-3 Glycine tert butyl ester hydrochloride

Reference