Detail of "27876-94-4"

Reference

Increasing fermentation yields

Increasing fermentation yields. Gainer, John L. (University of Virginia, USA). U.S. US 4038144 29 Jul 1977, 4 pp. (English). (United States of America). CODEN: USXXAM. CLASS: IC: C12B003-12. NCL: 195100000. APPLICATION: US 76-678113 19 Apr 1976. DOCUMENT TYPE: Patent CA Section: 16 (Fermentations) A method is described for increasing the yield of a fermn. process, based on adding a water-sol. carotenoid to the nutrient medium. Thus, the addn. of crocetin [27876-94-4] to the fermn. broth of Bacillus subtilis, Streptomyces griseus, and Trichoderma viride increased the yields of enzymes (20-30%), streptomycin [57-92-1] (25-50%), and cellulase [9012-54-8] (50-60%), resp.

Treating cerebral edema

Treating cerebral edema. Gainer, James V., Jr. (University of Virginia Patents Foundation, USA). U.S. US 4070460 24 Jan 1978, 3 pp. (English). (United States of America). CODEN: USXXAM. CLASS: IC: A61K031-70. NCL: 424180000. APPLICATION: US 75-630684 10 Nov 1975. DOCUMENT TYPE: Patent CA Section: 1 (Pharmacodynamics) Crocetin [27876-94-4] among other H2O-sol. carotenoids, is effective in the treatment of cerebral edema when applied i.v. or i.m. at a weekly dosage rate of from 0.001 to 1000 mg/kg. Pretreatment of cats with crocetin resulted in 80% redn. of edema after formation of a freezing lesion on the cortex, and 44% redn. of edema was obtained from posttreatment, compared to 49% and 36% redns., resp., when dexamethasone was used instead.