Detail of "2798-25-6"

CAS Number:
2798-25-6
Name:
9H-Xanthen-9-one,1,5,8-trihydroxy-3-methoxy-
Molecular Structure:
Formula:
C₁₄H₁₀O₆
Molecular Weight:
274.2256
Synonyms:
Xanthen-9-one,1,5,8-trihydroxy-3-methoxy- (7CI,8CI);1,5,8-Trihydroxy-3-methoxyxanthone;Bellidifodin;Bellidifolin;Bellidifolium;Bellidifoline;3-Methoxy-1,5,8-trihydroxyxanthone;1,5,8-Trihydroxy-3-methoxy-9H-xanthen-9-one;9H-xanthen-9-one, 1,5,8-trihydroxy-3-methoxy-;
Density:
1.586 g/cm³
Boiling Point:
580.2 °C at 760 mmHg
Flash Point:
228 °C

Display：

Assay:98% Appearance:yellow cryst... Package:10mg 20mgStorage:store in coo... Transportation:RT Application:reference su...

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Mutagenic activities of bellidifolin, methylbellidifolin, and methylswertianin in the methanol extract from Swertiae Herba (Gentianaceae): Mutagenic activities of bellidifolin, methylbellidifolin, and methylswertianin in the methanol extract from Swertiae Herba (Gentianaceae). Nozaka, Tomio; Morimoto, Isao; Watanabe, Fujio; Okitsu, Tomoaki (Saitama Prefect. Inst. Public Health, Urawa 338, Japan). Shoyakugaku Zasshi, 38(1), 96-101 (English) 1984. CODEN: SHZAAY. ISSN: 0037-4377. DOCUMENT TYPE: Journal CA Section: 63 (Pharmaceuticals) Section cross-reference(s): 4, 11 Methylbellidifolin (I, R1 = OMe, R2 = H) [521-65-3], methylswertianin (I, R1 = H, R2 = OMe) [22172-17-4] and bellidifolin (I, R1 = OH, R2 = H) [2798-25-6], isolated from the MeOH ext. of S. japonica had mutagenic activities of 520, 370 and 1382 revertants, resp., per 50 mg/plate and were not mutagenic unless activated by rat liver homogenate (59) mix in the Ames test. The mutagenicity of bellidifolin was 1.6-fold the activities of isogentisin and quercetin. The mutagenicity of methylbellidifolin was the same as the activities of isogentisin and quercetin. The activity is explained in terms of mol. structure-activity relationships. Thus, bellidifolin showing the strongest activity comprises 91% of the total hydroxyxanthones in Swertia herba.

Xanthones from Gentiana campestris as new acetylcholinesterase inhibitors: Xanthones from Gentiana campestris as new acetylcholinesterase inhibitors. Urbain, Aurelie; Marston, Andrew; Queiroz, Emerson Ferreira; Ndjoko, Karine; Hostettmann, Kurt (Laboratory of Pharmacognosy and Phytochemistry, Geneva-Lausanne School of Pharmacy, University of Lausanne, Lausanne, Switz.). Planta Medica, 70(10), 1011-1014 (English) 2004 Georg Thieme Verlag. CODEN: PLMEAA. ISSN: 0032-0943. DOCUMENT TYPE: Journal CA Section: 11 (Plant Biochemistry) Section cross-reference(s): 7 In order to discover new acetylcholinesterase (AChE) inhibitors, different plant exts. were screened by a previously established TLC bioautog. method. The methanol ext. of Gentiana campestris leaves exhibited significant inhibition of AChE activity.There are some commonly used reagents with their cas registry numbers 2798-25-6 and 54954-12-0 in this article. A bioactivity-guided fractionation approach was undertaken to isolate the active components. Four xanthones, bellidin, bellidifolin, bellidin 8-O-b-glucopyranoside (norswertianolin), and bellidifolin 8-O-b-glucopyranoside (swertianolin), were found to be responsible for the anti-AChE activity effects. Bellidifolin showed similar activity to galanthamine in this enzyme assay. .