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CAS No.: | 2899-60-7 |
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Name: | Z-GLY-OSU |
Article Data: | 33 |
Molecular Structure: | |
Formula: | C14H14N2O6 |
Molecular Weight: | 306.275 |
Synonyms: | Carbamicacid, [2-[(2,5-dioxo-1-pyrrolidinyl)oxy]-2-oxoethyl]-, phenylmethyl ester(9CI);Succinimide, N-[(N-carboxyglycyl)oxy]-, benzyl ester (7CI,8CI);Glycine,N-carboxy-, N-benzyl ester, O-succinimido deriv. (8CI);2,5-Pyrrolidinedione,1-[[[[(phenylmethoxy)carbonyl]amino]acetyl]oxy]-;CarbobenzoxyglycineN-hydroxysuccinimide ester;N-(Benzyloxycarbonyl)glycine N-hydroxysuccinimideester;N-(Benzyloxycarbonyl)glycine N-hydroxysuccinimidyl ester;N-Benzyloxycarbonyl-glycyl-N-hydroxysuccinimide ester;N-CarbobenzoxyglycineN-hydroxysuccinimide ester;2,5-dioxopyrrolidin-1-yl N-[(benzyloxy)carbonyl]glycinate;benzyl N-{2-[(2,5-dioxo-1-pyrrolidinyl)oxy]-2-oxoethyl}carbamate;glycine, N-[(phenylmethoxy)carbonyl]-, 2,5-dioxo-1-pyrrolidinyl ester;Succinimido (((benzyloxy)carbonyl)amino)acetate;Z-glycine N-succinimidyl ester; |
EINECS: | 220-789-7 |
Density: | 1.41g/cm3 |
Melting Point: | 111-115 °C |
Safety: | 22-24/25 |
PSA: | 102.01000 |
LogP: | 0.84880 |
The Glycine,N-[(phenylmethoxy)carbonyl]-, 2,5-dioxo-1-pyrrolidinyl ester, with the CAS registry number 2899-60-7 and EINECS registry number 220-789-7, has the systematic name of 2,5-dioxopyrrolidin-1-yl N-[(benzyloxy)carbonyl]glycinate. It belongs to the following product categories: Amino Acid Derivatives; Z-Amino Acids and Derivatives; Z-Amino acid series. And it should be stored at 2-8°C. What's more, while dealing with this chemical, you had better not breathe dust and then try to avoid contacting with skin and eyes. The molecular formula of the chemical is C14H14N2O6.
The characteristics of Glycine,N-[(phenylmethoxy)carbonyl]-, 2,5-dioxo-1-pyrrolidinyl ester are as followings: (1)ACD/LogP: -0.15; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): -0.15; (4)ACD/LogD (pH 7.4): -0.15; (5)ACD/BCF (pH 5.5): 1; (6)ACD/BCF (pH 7.4): 1; (7)ACD/KOC (pH 5.5): 19.64; (8)ACD/KOC (pH 7.4): 19.61; (9)#H bond acceptors: 8; (10)#H bond donors: 1; (11)#Freely Rotating Bonds: 7; (12)Polar Surface Area: 93.22 Å2; (13)Index of Refraction: 1.589; (14)Molar Refractivity: 73.23 cm3; (15)Molar Volume: 217.1 cm3; (16)Polarizability: 29.03×10-24cm3; (17)Surface Tension: 62.5 dyne/cm; (18)Density: 1.41 g/cm3.
Preparation of Glycine,N-[(phenylmethoxy)carbonyl]-, 2,5-dioxo-1-pyrrolidinyl ester: This chemical can be prepared by N-hydroxy-succinimide and N-benzyloxycarbonyl-glycine. The reaction will need reagent1,3-dicyclohexylcarbodiimide (DCC), and the menstruum tetrahydrofuran. The reaction time is 3 hours with heating, and the yield is about 0%.
Uses of Glycine,N-[(phenylmethoxy)carbonyl]-, 2,5-dioxo-1-pyrrolidinyl ester: It can react with cyanamide to produce N-carbobenzoxyglycylcyanamide. This reaction will need reagent aq. NaOH, and the menstruum tetrahydrofuran. And the yield is about 43%.
Addtionally, the following datas could be converted into the molecular structure:
(1)SMILES: O=C2N(OC(=O)CNC(=O)OCc1ccccc1)C(=O)CC2
(2)InChI: InChI=1/C14H14N2O6/c17-11-6-7-12(18)16(11)22-13(19)8-15-14(20)21-9-10-4-2-1-3-5-10/h1-5H,6-9H2,(H,15,20)
(3)InChIKey: WSCWXNZWFZXKEH-UHFFFAOYAW