Detail of "2912-62-1"

Reference

Proximity effects in fused cyclobutanones

Proximity effects in fused cyclobutanones. Facile formation of cage systems. Hassner, A.; Naidorf-Meir, Simha; Gottlieb, H. E.; Goldberg, I. (Dep. Chem., Bar-Ilan Univ.There are some reagents with their cas registry numbers 110-87-2 and 2912-62-1 are used in this study., Ramat Gan 52100, Israel). J. Org. Chem., 57(8), 2442-5 (English) 1992. CODEN: JOCEAH. ISSN: 0022-3263. DOCUMENT TYPE: Journal CA Section: 22 (Physical Organic Chemistry) Section cross-reference(s): 75 Chlorobicyclooctanone (I) on reaction with H2O-Et3N in acetonitrile at 20° produced in high yield four complex dimeric compds. (II, III, IV, V). The novel structures produced by C-C bond formation between tertiary centers were revealed by NMR and x-ray diffraction. Pathways leading from II or its diastereomer to cage compds. III or V indicate the importance of proximity effects in these transformations. .

Pyrrylphenylethanones related to cathinone and lefetamine: synthesis and pharmacological activities

Pyrrylphenylethanones related to cathinone and lefetamine: synthesis and pharmacological activities. Massa, Silvio; Di Santo, Roberto; Mai, Antonello; Artico, Marino; Pantaleoni, Gian Carlo; Giorgi, Raffaele; Coppolino, Maria Francesca (Dip. Stud. Farm., Univ. Roma "La Sapienza", Rome I-00185, Italy). Arch. Pharm. (Weinheim, Ger.), 325(7), 403-9 (English) 1992. CODEN: ARPMAS. ISSN: 0365-6233. 2912-62-1 is also in the experiment. DOCUMENT TYPE: Journal CA Section: 26 (Biomolecules and Their Synthetic Analogs) Section cross-reference(s): 1 The synthesis of various pyrrylphenylethanones, i.e., I (R = NMe2, NEt2, NHC6H4OEt-4, NHCH2C6H3Cl2-2,4) resembling cathinone and lefetamine is described starting from chloroethanone I (R = Cl). Some derivs. showed good antinociceptic activity, comparable to that of morphine. The neuropsychopharmacol. profile of title compds. has been also studied to explore their action on C.N.S. .