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Detail of "2942-59-8"

  • CAS Number:
  • 2942-59-8
  • Name:

  • 2-Chloronicotinic acid

  • Molecular Structure:
  • Formula:
  • C6H4ClNO2
  • Molecular Weight:
  • 157.56
  • Synonyms:
  • 3-Pyridinecarboxylic acid, 2-chloro-;Nicotinic acid, 2-chloro-;2-chloropyridine-3-carboxylic acid;2-chloropyridine-3-carboxylate;2-Chloro-3-pyridinecarboxylic acid;2-chloro-3-pyridine carboxylic acid;2,3-Pyridinedicarboxylic anhydride;2-Chloro-nicotinic acid;
  • EINECS:
  • 220-937-0
  • Density:
  • 1.47 g/cm3
  • Melting Point:
  • 176-178 °C (dec.)(lit.)
  • Boiling Point:
  • 316.8 °C at 760 mmHg
  • Flash Point:
  • 145.4 °C
  • Appearance:
  • white to cream powder
  • Hazard Symbols:
  • IrritantXi
  • Risk Codes:
  • 36/37/38
  • Safety:
  • 22-24/25-37/39-26-36 Details
  • particular:
  • particular
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CAS No.2942-59-8 2-Chloronicotinic acidCompetitive Product

Assay:≥99.2%（HPLC）  Appearance:white to sli...  Package:25kgs/drum,o...

m.p.：≥177℃-180℃ 6-chloronicotinic acid：≤ 0.1%（HPLC） Ignition residue：≤ 0.1% Drying Loss： ≤ 0.3% 【Packing】：In fibre drum,lined with double plastic bag,net weight:25kgs/drum,or according to the customer’s requirement

Supplier:Zhejiang Rongkai Chemical Technology Co.,Ltd. [ China (Mainland)]

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CAS No.2942-59-8 2-Chloronicotinic acidCompetitive Product

Assay:above 98%  Appearance:white or alm...  Package:25kg/fibre d...

product name:2-Chloronicotinic acid Another name:2-Chloro-3-pyridinecarboxylic acid CAS NO.:2942-59-8 Mol Structure: Mol Fm: C6H4ClNO2 Mol Wt: 157.56 Char:white or prime white crystal power package :25kg per barrel assay:≥99% Application:organo-fluorine intermediates

Supplier:Jinan Decheng Hemu Medical Technology Co.，Ltd. [ China (Mainland)]

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CAS No.2942-59-8 2-Chloronicotinic acidCompetitive Product

Assay:≥99.5%  Appearance:white or off...

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CAS No.2942-59-8 2-Chloronicotinic acid

2-Chloronicotinic acid

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CAS No.2942-59-8 2-Chloronicotinic acid

Assay:99.5%  Appearance:powder  Package:25kg/drumStorage:1-10MT

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CAS No.2942-59-8 2-Chloronicotinic acid

  Appearance:colorless so...  Transportation:sea transpor...

MOL File: 2942-59-8.mol It is colorless solid, m.p. > 175 ℃ (breakdown).It is insoluble in water, but soluble in organic solvent, benzene, toluene, etc.

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CAS No.2942-59-8 2-Chloronicotinic acid

  Appearance:White crysta...  Package:25kg  Application:Pharmaceutic...

2-Chloronicotinic acid Formula: C8H4CINO2 Molecular Weight: 157.5

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CAS No.2942-59-8 2-Chloronicotinic acid

Assay:99% min  Appearance:white to off...

Product name:2-CHLORLPYRIDINE-3-CARBOXYLIC ACID Loss on drying: 0.5% max

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CAS No.2942-59-8 2-Chloronicotinic acid

Assay:99%min  Appearance:White crysta...  Package:On request

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CAS No.2942-59-8 2-Chloronicotinic acid

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CAS No.2942-59-8 2-Chloronicotinic acid

2-Chloronicotinic acid Appearance: white to slight yellow crystalline powder Purity：≥99.2%（HPLC） m.p.：≥177℃-180℃ 6-chloronicotinic acid：≤ 0.1%（HPLC） Ignition residue：≤ 0.1% Drying Loss： ≤ 0.3%

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Assay:99%  Appearance:White to cre...

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CAS No.2942-59-8 2-Chloronicotinic acid

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Assay:98%

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CAS No.2942-59-8 2-Chloronicotinic acid

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CAS No.2942-59-8 2-Chloronicotinic acid

Assay:99.5%min(HPL...  Appearance:White crysta...  Package:25KG net/per...

C-4644 2-Chloronicotinic acid M.F:C6H4ClNO2

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Reference

Antinflammatory and analgesic pharmaceuticals containing nicotinic acid derivatives
Antinflammatory and analgesic pharmaceuticals containing nicotinic acid derivatives. Sherlock, Margaret H.; Sperber, Nathan (Scherico Ltd., USA). Japan. JP 51005386 B4 19 Feb 1976 Showa, 19 pp. (Japanese). (Japan). CODEN: JAXXAD. CLASS: IC: C07D213-80. APPLICATION: JP 66-13745 7 Mar 1966. DOCUMENT TYPE: Patent CA Section: 63 (Pharmaceuticals) Pharmaceuticals contg. 2-(2-methyl-3-chloroanilino)nicotinic acid (I) [17737-65-4] and 2-(2-methyl-3-trifluoromethylanilino)nicotinic acid (II) [38677-85-9] or their derivs. are antiinflammatory and analgesic. These compds. are prepd. by treating III with IV or V (R = H or other groups which will not hinder the reaction; Q = halogens, alkoxy, alkylthio, alkoxysulfonyl, nitro, or substituted or unsubstituted amino groups; T = halogens or substituted or unsubstituted amino groups). E.g., 2-chloronicotinic acid [2942-59-8] was treated with 2-methyl-3-chloroaniline [87-60-5] to give I. A tablet prepn. consisted of I, citric acid, lactose, CaHPO4, Pluronic F-68, Na lurylsulfate, poly(vinyl pyrrolidone), Carbowax 1500, Carbowax 6000, denatured alc., corn starch, and Mg stearate.
Purity assay of niflumic acid by reversed-phase high-performance liquid chromatography
Purity assay of niflumic acid by reversed-phase high-performance liquid chromatography. Guechot, C.; Nicolle, P. (Carpibem, Rueil-Malmaison 92500, Fr.). J. Chromatogr., 303(2), 440-3 (English) 1984. CODEN: JOCRAM. ISSN: 0021-9673. DOCUMENT TYPE: Journal CA Section: 64 (Pharmaceutical Analysis) 2-Chloronicotinic acid (I) [2942-59-8] and 2-hydroxy-N-[(3-trifluoromethyl)phenyl]nicotinamide (II) [72633-64-8] were detd. in niflumic acid (III) [4394-00-7] by chromatog. on a methyloctylsilyl column with MeOH-0.1% H3PO4 () with detection at 267, 330, and 289 nm, resp. The sensitivity for I and II was <5 ng, and the relative std. deviations were 2.3-3.9 and 1.4 and 2.4%, resp. Assay of 5 com. batches of III indicated 0.02-0.07% I and 0.24-0.96% II.
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