Reference

The effectivity of 1H-triazoles and -tetrazoles as activators in acid-catalyzed phosphoramidite alcoholysis

The effectivity of 1H-triazoles and -tetrazoles as activators in acid-catalyzed phosphoramidite alcoholysis. Nurminen, Erkki J.; Mattinen, Jorma K.; Loennberg, Harri (Department of Chemistry, University of Turku, Turun Yliopisto 20014, Finland). Helvetica Chimica Acta, 86(6), 2005-2008 (English) 2003 Verlag Helvetica Chimica Acta. CODEN: HCACAV. ISSN: 0018-019X. DOCUMENT TYPE: Journal CA Section: 29 (Organometallic and Organometalloidal Compounds) Section cross-reference(s): 22 The efficiency of 5-nitro-1,2,4-1H-triazole (3), 5-(methylthio)-1H-tetrazole (4), and 5-(4-nitrophenyl)-1H-tetrazole (5) as activators in phosphoramidite alcoholysis was studied relative to 1H-tetrazole (6). Reactions of these azoles with diisopropyl (diisopropylamido)phosphite (1a) were followed in THF, and the rates increased with increasing acidity of the azoles. The Bronsted a value of 0.7 detd. 211055-34-4 and 29515-99-9 are just another two chemicals used in this study. for this dependence is in agreement with data published earlier. .