Detail of "298-08-8"

Reference

Levels of urinary

Levels of urinary .alpha.-amino ketones in amino acid supplementation of a protein. Kanbe, Tamotsu; Oshiba, Keiichi (Osaka City Inst. Public Health Environ. Sci., Osaka, Japan). Eiyo To Shokuryo, 29(9), 491-6 (Japanese) 1976. CODEN: EISOAU. DOCUMENT TYPE: Journal CA Section: 18 (Animal Nutrition) Male weanling rats were fed a basal diet contg. 7.5% casein and 3.85% L-amino acids. Supplementation of L-threonine [72-19-5] to the basal diet increased the level of urinary .alpha.-amino ketones esp. aminoacetone [298-08-8]. Supplementation of glycine did not elevate the urinary amino ketones level, nor did methionine, lysine, or tryptophan, alone or in combinations.

Use of ethyl acetoacetate for determination of a-amino ketones

Use of ethyl acetoacetate for determination of a-amino ketones. Molenda, Marta; Szoltysek, Henryk; Szczebara, Marianna (Zakl. Toksykol.Several substances are used for example 141-97-9 and 2199-51-1 which are their cas registry numbers., Slaska Akad. Med., Katowice, Pol.). Bromatol. Chem. Toksykol., 16(3-4), 263-7 (Polish) 1983. CODEN: BCTKAG. ISSN: 0365-9445. DOCUMENT TYPE: Journal CA Section: 4 (Toxicology) The anal. of a-amino ketone pyrroles, formed from the condensation of urinary aminoacetone [298-08-8] and d-aminolevulinic acid [106-60-5] with Et acetylacetate [141-97-9], instead of acetylacetone, was given. Using Sephadex G-15 column, the dependence of an elution vol. of 2-methyl-3-carboethoxy-4-pyrrolepropionic acid (I) [38664-16-3] and 2,4-dimethyl-3-carboethoxypyrrole (II) [2199-51-1] upon pH was studied. These derivs. were divided well at alk. pH, just as 2,4-dimethyl-3-acetylpyrrole (III) [2386-25-6] and 2-methyl-3-acetyl-4-pyrrolepropionic acid (IV) [38664-17-4], which were formed from the condensation of aminoacetone and d-aminolevulinate with acetylacetone. Unlike I, III did not change markedly in its elution vol. on Sephadex G-15. The behavior of I, II, III, and IV in respect to condensation time, amts. of acetylacetone and Et acetylacetate added to the condensation mixt., and the color constancy following the addn. of Ehrlich reagent, were compared. In the case of Et acetylacetate, the condensation time may be detd. with a large tolerance margin; whereas for compds. condensed with acetylacetone, the condensation time has to be exactly defined. .